ZYX Products
(Zyxin (ZYX))
Categories
Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Jul 2008].
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Featured ZYX Categories
ZYX Antibodies
High quality antibodies with extensive validation data.
ZYX ELISA Kits
Reliable ELISA kits for a wide range of species.
ZYX Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ZYX Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IP, RNAi
Validations
- (2)
- (6)
Cat. No.
ABIN563471
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (5)
Cat. No.
ABIN6266149
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (1)
- (4)
Cat. No.
ABIN521634
Quantity
100 μg
Datasheet
Datasheet
Recommended ZYX ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960598
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6975027
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1168973
Quantity
96 tests
Datasheet
Datasheet
Recommended ZYX Proteins
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Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125821
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1326572
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7396079
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our ZYX products
: "Substrate engagement of integrins α5β1 and αvβ3 is necessary, but not sufficient, for high directional persistence in migration on fibronectin." in: Scientific reports, Vol. 6, pp. 23258, (2016) (PubMed).: "NBR1 enables autophagy-dependent focal adhesion turnover." in: The Journal of cell biology, Vol. 212, Issue 5, pp. 577-90, (2016) (PubMed).
: "α-Actinin-4 enhances colorectal cancer cell invasion by suppressing focal adhesion maturation." in: PLoS ONE, Vol. 10, Issue 4, pp. e0120616, (2015) (PubMed).
: "Cell shape-dependent early responses of fibroblasts to cyclic strain." in: Biochimica et biophysica acta, Vol. 1833, Issue 12, pp. 3415-25, (2013) (PubMed).
: "Zyxin is a transforming growth factor-? (TGF-?)/Smad3 target gene that regulates lung cancer cell motility via integrin ?5?1." in: The Journal of biological chemistry, Vol. 287, Issue 37, pp. 31393-405, (2012) (PubMed).
: "Cell-penetrating peptides with intracellular actin-remodeling activity in malignant fibroblasts." in: The Journal of biological chemistry, Vol. 285, Issue 10, pp. 7712-21, (2010) (PubMed).
: "Domain analysis of alpha-actinin reveals new aspects of its association with F-actin during cytokinesis." in: Experimental cell research, Vol. 316, Issue 12, pp. 1925-34, (2010) (PubMed).
: "Zyxin mediates actin fiber reorganization in epithelial-mesenchymal transition and contributes to endocardial morphogenesis." in: Molecular biology of the cell, Vol. 20, Issue 13, pp. 3115-24, (2009) (PubMed).
: "mTOR regulates expression of slit diaphragm proteins and cytoskeleton structure in podocytes." in: American journal of physiology. Renal physiology, Vol. 296, Issue 2, pp. F418-26, (2009) (PubMed).
: "Targeted disruption of the mouse Lipoma Preferred Partner gene." in: Biochemical and biophysical research communications, Vol. 379, Issue 2, pp. 368-73, (2009) (PubMed).
Synonyms and alternative names related to ZYX
Zyxin (zyx-1), Zyxin (Zyx), zyxin (zyx), zyxin (ZYX), zyxin (EDI_201420), zyxin (Zyx), zyxin S homeolog (zyx.S), 9530098H06Rik, BcDNA:LD06023, CG32018, DLim-1, Dmel\\CG32018, DmLIM-1, ESP-2, HED-2, lim, Lim102EF, MGC145270, R75157, zgc:171680, ZYX, zyx, ZYX102, Zyx102, zyx102, Zyx102EF, zyxinProtein level used designations for ZYX
- ZYXin family member (zyx-1)
- CG32018-PA
- CG32018-PB
- CG32018-PG
- CG32018-PH
- Zyx-PA
- Zyx-PB
- Zyx-PG
- Zyx-PH
- Zyx102EF
- zyxin
- hypothetical protein LOC779718
- zyxin-2
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