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Zona Pellucida Glycoprotein 3 Products

(Zona Pellucida Glycoprotein 3 (ZP3))

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The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene is a structural component of the zona pellucida and functions in primary binding and induction of the sperm acrosome reaction. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a C-terminal consensus furin cleavage site, and a transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. A variation in the last exon of this gene has previously served as the basis for an additional ZP3 locus\; however, sequence and literature review reveals that there is only one full-length ZP3 locus in the human genome. Another locus encoding a bipartite transcript designated POMZP3 contains a duplication of the last four exons of ZP3, including the above described variation, and maps closely to this gene. [provided by RefSeq, Jul 2008].

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Featured Zona Pellucida Glycoprotein 3 Categories

Zona Pellucida Glycoprotein 3 Antibodies

High quality antibodies with extensive validation data.

Zona Pellucida Glycoprotein 3 ELISA Kits

Reliable ELISA kits for a wide range of species.

Zona Pellucida Glycoprotein 3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Zona Pellucida Glycoprotein 3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application IF
Validations
  • (6)
Cat. No. ABIN7256676
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN6150536
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN6150537
Quantity 100 μL
Datasheet Datasheet

Recommended Zona Pellucida Glycoprotein 3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6971230
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5594022
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method
Validations
Cat. No. ABIN1168931
Quantity 96 tests
Datasheet Datasheet

Recommended Zona Pellucida Glycoprotein 3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN6964410
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7490852
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125817
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our Zona Pellucida Glycoprotein 3 products

Ling, Feng, Wei, Wang, Wang, Wang, Tang, Luo, Xiong: "Human amnion-derived mesenchymal stem cell (hAD-MSC) transplantation improves ovarian function in rats with premature ovarian insufficiency (POI) at least partly through a paracrine mechanism." in: Stem cell research & therapy, Vol. 10, Issue 1, pp. 46, (2019) (PubMed).

Amorim, Moya, Donnez, Dolmans: "Morphometric characteristics of preantral and antral follicles and expression of factors involved in folliculogenesis in ovaries of adult baboons (Papio anubis)." in: Journal of assisted reproduction and genetics, Vol. 33, Issue 5, pp. 617-626, (2016) (PubMed).

Mask, Schoenecker, Kane, Ransom, Bruemmer: "Serum antibody immunoreactivity to equine zona protein after SpayVac vaccination." in: Theriogenology, Vol. 84, Issue 2, pp. 261-7, (2015) (PubMed).

Törmälä, Jääskeläinen, Lakkakorpi, Liakka, Tapanainen, Vaskivuo: "Zona pellucida components are present in human fetal ovary before follicle formation." in: Molecular and cellular endocrinology, Vol. 289, Issue 1-2, pp. 10-5, (2008) (PubMed).

Synonyms and alternative names related to Zona Pellucida Glycoprotein 3

zona pellucida glycoprotein 3 (ZP3), zona pellucida glycoprotein 3 (zp3), zona pellucida glycoprotein 3 (Zp3), zona pellucida sperm-binding protein 3 (ZP3), Zp-3, Zp-3B, zp3.2, ZP3A, ZP3B, ZPC

Protein level used designations for Zona Pellucida Glycoprotein 3

  • ZP3A/ZP3B
  • sperm receptor
  • zona pellucida glycoprotein 3A (sperm receptor)
  • zona pellucida glycoprotein 3B
  • zona pellucida glycoprotein ZP3
  • zona pellucida protein C
  • zona pellucida sperm-binding protein 3
  • zona pellucida 3 glycoprotein (sperm receptor)
  • zona pellucida C
  • zona pellucida glycoprotein 3.2
  • zona pellucida glycoprotein 3 preproprotein
  • zona pellucida glycoprotein ZP3B
  • zona pellucida 3 glycoprotein
  • zona pellucida glycoprotein C
  • zona pellucida C protein
  • zona pellucida glycoprotein 3 (sperm receptor)
  • zona pellucida glycoprotein 3-beta
  • zona pellucida glycoprotein ZP3-beta
  • zona pellucida protein 3-beta
  • zp-3-beta
  • zp3-beta
  • Sperm receptor
  • Zona pellucida protein C
  • glycoprotein hZP3
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