ZNF521 Products
(Zinc Finger Protein 521 (ZNF521))
Categories
Transcription factor that can both act as an activator or a repressor depending on the context. Involved in BMP signaling and in the regulation of the immature compartment of the hematopoietic system. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved specification of B-cell lineage\; this interaction preventing EBF1 to bind DNA and activate target genes.
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Featured ZNF521 Categories
ZNF521 Antibodies
High quality antibodies with extensive validation data.
Recommended ZNF521 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN1804181
Quantity
0.05 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN7271496
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, EIA, IF
Validations
- (2)
Cat. No.
ABIN1449926
Quantity
0.1 mg
Datasheet
Datasheet
Recommended ZNF521 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3096488
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our ZNF521 products
: "Zfp521 promotes B-cell viability and cyclin D1 gene expression in a B cell culture system." in: Leukemia research, Vol. 46, pp. 10-7, (2016) (PubMed).: "Direct transcriptional repression of Zfp423 by Zfp521 mediates a bone morphogenic protein-dependent osteoblast versus adipocyte lineage commitment switch." in: Molecular and cellular biology, Vol. 34, Issue 16, pp. 3076-85, (2014) (PubMed).
: "Critical role of zinc finger protein 521 in the control of growth, clonogenicity and tumorigenic potential of medulloblastoma cells." in: Oncotarget, Vol. 4, Issue 8, pp. 1280-92, (2013) (PubMed).
Synonyms and alternative names related to ZNF521
zinc finger protein 521 (Zfp521), zinc finger protein 521 (ZNF521), zinc finger protein 521 S homeolog (znf521.S), B930086A16Rik, EHZF, Evi3, Znf521Protein level used designations for ZNF521
- LYST-interacting protein 3
- early hematopoietic zinc finger protein
- ecotropic viral integration site 3 protein
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