ZNF207 Products
(Zinc Finger Protein 207 (ZNF207))
Categories
Kinetochore- and microtubule-binding protein that plays a key role in spindle assembly. ZNF207/BuGZ is mainly composed of disordered low-complexity regions and undergoes phase transition or coacervation to form temperature-dependent liquid droplets. Coacervation promotes microtubule bundling and concentrates tubulin, promoting microtubule polymerization and assembly of spindle and spindle matrix by concentrating its building blocks (PubMed:26388440). Also acts as a regulator of mitotic chromosome alignment by mediating the stability and kinetochore loading of to a first report, ZNF207/BuGZ may act by blocking ubiquitination and proteasomal degradation of BUB3. According to another report, the stabilization is independent of the proteasome (By similarity). {ECO:0000250|UniProtKB:O43670, ECO:0000269|PubMed:26388440}.
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Featured ZNF207 Categories
ZNF207 Antibodies
High quality antibodies with extensive validation data.
ZNF207 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ZNF207 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (6)
Cat. No.
ABIN563462
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, RNAi
Validations
- (6)
Cat. No.
ABIN563465
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (4)
Cat. No.
ABIN563457
Quantity
100 μg
Datasheet
Datasheet
Recommended ZNF207 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1325975
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1325977
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2735957
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our ZNF207 products
: "Splicing function of mitotic regulators links R-loop-mediated DNA damage to tumor cell killing." in: The Journal of cell biology, Vol. 209, Issue 2, pp. 235-46, (2015) (PubMed).Synonyms and alternative names related to ZNF207
zinc finger protein 207 (Zfp207), zinc finger protein 207 (znf207), zinc finger protein 207 (ZNF207), zinc finger protein 207, b (znf207b), zinc finger protein 207 S homeolog (znf207.S), zinc finger protein 207, a (znf207a), 4m77, MGC75627, MGC116398, wu:fa03f07, wu:fb50g07, wu:fb51h09, wu:fc17a09, wu:fc17a10, wu:fj12e11, Zfp207, zgc:56601, zgc:77832, ZNF207, znf207Protein level used designations for ZNF207
- zinc finger protein 207
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