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ZIC1 Products

(Zinc Finger Protein ZIC 1 (ZIC1))

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This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development. Aberrant expression of this gene is seen in medulloblastoma, a childhood brain tumor. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 4, a related family member on chromosome 3. This gene encodes a transcription factor that can bind and transactivate the apolipoprotein E gene. [provided by RefSeq, Jul 2008].

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Featured ZIC1 Categories

ZIC1 Antibodies

High quality antibodies with extensive validation data.

ZIC1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ZIC1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN521454
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN521456
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN521453
Quantity 100 μg
Datasheet Datasheet

Recommended ZIC1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1325788
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3076139
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN2735882
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our ZIC1 products

He, Yu, Lu, Wang, Wu, Zhao, Li, Zhou, Liu, Mu, Xin, Qiu, Lu: "Transcriptional Regulator ZEB2 Is Essential for Bergmann Glia Development." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 38, Issue 6, pp. 1575-1587, (2019) (PubMed).

Sankar, Yellajoshyula, Zhang, Teets, Rockweiler, Kroll: "Gene regulatory networks in neural cell fate acquisition from genome-wide chromatin association of Geminin and Zic1." in: Scientific reports, Vol. 6, pp. 37412, (2018) (PubMed).

Di Giovannantonio, Di Salvio, Omodei, Prakash, Wurst, Pierani, Acampora, Simeone: "Otx2 cell-autonomously determines dorsal mesencephalon versus cerebellum fate independently of isthmic organizing activity." in: Development (Cambridge, England), Vol. 141, Issue 2, pp. 377-88, (2014) (PubMed).

He, Zhang, Chen, Remke, Shih, Lu, Wang, Deng, Yu, Xia, Wu, Ramaswamy, Hu, Wang, Zhou, Burns, Kim, Kool, Pfister, Weinstein, Pomeroy, Gilbertson, Rubin, Hou, Wechsler-Reya, Taylor, Lu: "The G protein α subunit Gαs is a tumor suppressor in Sonic hedgehog-driven medulloblastoma." in: Nature medicine, Vol. 20, Issue 9, pp. 1035-42, (2014) (PubMed).

Simões-Costa, McKeown, Tan-Cabugao, Sauka-Spengler, Bronner: "Dynamic and differential regulation of stem cell factor FoxD3 in the neural crest is Encrypted in the genome." in: PLoS genetics, Vol. 8, Issue 12, pp. e1003142, (2013) (PubMed).

Zhou, Jiang, Gu, Tang, Shen, Jin: "MicroRNA-195 targets ADP-ribosylation factor-like protein 2 to induce apoptosis in human embryonic stem cell-derived neural progenitor cells." in: Cell death & disease, Vol. 4, pp. e695, (2013) (PubMed).

Siegenthaler, Choe, Patterson, Hsieh, Li, Jaminet, Daneman, Kume, Huang, Pleasure: "Foxc1 is required by pericytes during fetal brain angiogenesis." in: Biology open, Vol. 2, Issue 7, pp. 647-59, (2013) (PubMed).

Lipchina, Elkabetz, Hafner, Sheridan, Mihailovic, Tuschl, Sander, Studer, Betel: "Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response." in: Genes & development, Vol. 25, Issue 20, pp. 2173-86, (2011) (PubMed).

Zhao, Ayrault, Zindy, Kim, Roussel: "Post-transcriptional down-regulation of Atoh1/Math1 by bone morphogenic proteins suppresses medulloblastoma development." in: Genes & development, Vol. 22, Issue 6, pp. 722-7, (2008) (PubMed).

Aruga, Shimoda, Mikoshiba: "A 5' segment of the mouse Zic1 gene contains a region specific enhancer for dorsal hindbrain and spinal cord." in: Brain research. Molecular brain research, Vol. 78, Issue 1-2, pp. 15-25, (2000) (PubMed).

Synonyms and alternative names related to ZIC1

Zic family member 1 (ZIC1), Zic family member 1 (Zic1), Zic family member 1 S homeolog (zic1.S), zinc finger protein of the cerebellum 1 (Zic1), opl, ZIC, ZNF201

Protein level used designations for ZIC1

  • Zic family member 1 (odd-paired homolog, Drosophila)
  • Zinc finger protein of the cerebellum 1
  • zinc finger protein 201
  • zinc finger protein ZIC 1
  • zic protein member 1
  • zinc finger protein of the cerebellum 1
  • XZic1
  • ZIC-r1
  • ZIC-related protein 1
  • Zic family member 1 (odd-paired homolog)
  • Zic-related-1
  • xlZic1
  • xopl
  • odd-paired homolog
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