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ZEB2 Products

(Zinc Finger E-Box Binding Homeobox 2 (ZEB2))
The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jan 2010].

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Featured ZEB2 Categories

ZEB2 Antibodies

High quality antibodies with extensive validation data.

ZEB2 ELISA Kits

Reliable ELISA kits for a wide range of species.

ZEB2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ZEB2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (5)
Cat. No. ABIN7261656
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (2)
  • (3)
Cat. No. ABIN523264
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Guinea Pig, Horse, Human, Mouse, Pig, Rat, Zebrafish (Danio rerio)
Application WB, IHC
Validations
  • (3)
  • (4)
Cat. No. ABIN2780948
Quantity 100 μL
Datasheet Datasheet

Recommended ZEB2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6971220
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960587
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN5648247
Quantity 96 tests
Datasheet Datasheet

Recommended ZEB2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125773
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7399877
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3096498
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our ZEB2 products

Ordonez, Hay, McEwen, Polanska, Hughes, Delpuech, Cadogan, Powell, Dry, Tornillo, Silcock, Leo, OConnor, Clarke, Smalley: "Rapid activation of epithelial-mesenchymal transition drives PARP inhibitor resistance in Brca2-mutant mammary tumours." in: Oncotarget, Vol. 10, Issue 27, pp. 2586-2606, (2019) (PubMed).

Feng, Cai, Li, Jian, Zhang, Li: "Tripartite motif-containing 14 (TRIM14) promotes epithelial-mesenchymal transition via ZEB2 in glioblastoma cells." in: Journal of experimental & clinical cancer research : CR, Vol. 38, Issue 1, pp. 57, (2019) (PubMed).

Wang, Liu, Han, Dai, Ni, Xiao, Huang: "Downregulated lncRNA UCA1 acts as ceRNA to adsorb microRNA-498 to repress proliferation, invasion and epithelial mesenchymal transition of esophageal cancer cells by decreasing ZEB2 expression." in: Cell cycle (Georgetown, Tex.), Vol. 18, Issue 18, pp. 2359-2376, (2019) (PubMed).

Ding, Tang, Fan, Wang, Wu, Xu, Xu, Gao, Wu: "Overexpression of PEAK1 contributes to epithelial-mesenchymal transition and tumor metastasis in lung cancer through modulating ERK1/2 and JAK2 signaling." in: Cell death & disease, Vol. 9, Issue 8, pp. 802, (2018) (PubMed).

Yang, Toledo, Rosmaninho, Peng, Uhlén, Castro, Arenas: "A Zeb2-miR-200c loop controls midbrain dopaminergic neuron neurogenesis and migration." in: Communications biology, Vol. 1, pp. 75, (2018) (PubMed).

Cichocki, Valamehr, Bjordahl, Zhang, Rezner, Rogers, Gaidarova, Moreno, Tuininga, Dougherty, McCullar, Howard, Sarhan, Taras, Schlums, Abbot, Shoemaker, Bryceson, Blazar, Wolchko, Cooley, Miller: "GSK3 Inhibition Drives Maturation of NK Cells and Enhances Their Antitumor Activity." in: Cancer research, Vol. 77, Issue 20, pp. 5664-5675, (2017) (PubMed).

Hoshi, Endo, Shirakihara, Fukagawa, Miyazawa, Saitoh: "The potential role of regulator of G-protein signaling 16 in cell motility mediated by δEF1 family proteins." in: FEBS letters, Vol. 590, Issue 2, pp. 270-8, (2016) (PubMed).

Lee, Wang, Yumoto, Jung, Cackowski, Decker, Li, Franceschi, Pienta, Taichman: "DNMT1 Regulates Epithelial-Mesenchymal Transition and Cancer Stem Cells, Which Promotes Prostate Cancer Metastasis." in: Neoplasia (New York, N.Y.), Vol. 18, Issue 9, pp. 553-66, (2016) (PubMed).

Yasumi, Inoue, Maruhashi, Kamachi, Higashi, Kondoh, Uchikawa: "Regulation of trunk neural crest delamination by δEF1 and Sip1 in the chicken embryo." in: Development, growth & differentiation, Vol. 58, Issue 2, pp. 205-14, (2016) (PubMed).

Xu, Zhu, Zhao, Chen, Zhang, Yuan, Deng, Dou, Wang, Huang, Chen, Jiang, Yu: "Atypical ubiquitin E3 ligase complex Skp1-Pam-Fbxo45 controls the core epithelial-to-mesenchymal transition-inducing transcription factors." in: Oncotarget, Vol. 6, Issue 2, pp. 979-94, (2015) (PubMed).

Synonyms and alternative names related to ZEB2

zinc finger E-box binding homeobox 2 (ZEB2), zinc finger E-box binding homeobox 2 (Zeb2), zinc finger E-box binding homeobox 2 S homeolog (zeb2.S), zinc finger homeobox protein (zeb2), zinc finger E-box binding homeobox 2a (zeb2a), zinc finger E-box binding homeobox 2b (zeb2b), 9130203F04Rik, D130016B08Rik, HSPC082, mKIAA0569, si:dkey-52o2.2, SIP-1, SIP1, sip1, sip1a, sip1b, SMADIP1, wu:fc92g08, XSip1, ZFHX1B, Zfhx1b, zfhx1b, Zfx1b, Zfxh1b

Protein level used designations for ZEB2

  • zinc finger homeobox 1b
  • zinc finger E-box-binding homeobox 2
  • SMAD interacting protein 1
  • Smad-interacting protein 1
  • smad-interacting protein 1
  • zinc finger homeobox protein 1b
  • smad interaction protein 1
  • zinc finger E-box binding homeobox 2
  • zinc finger homeobox protein
  • Smad-interacting protein-1a
  • transcription factor SIP1a
  • zeb2
  • Smad-interacting protein-1b
  • transcription factor SIP1b
  • zfhx1b
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