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YARS2 Products

(Tyrosyl-tRNA Synthetase 2, Mitochondrial (YARS2))

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This gene encodes a mitochondrial protein that catalyzes the attachment of tyrosine to tRNA(Tyr). Mutations in this gene are associated with myopathy with lactic acidosis and sideroblastic anemia type 2 (MLASA2). [provided by RefSeq, Jan 2011].

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Featured YARS2 Categories

YARS2 Antibodies

High quality antibodies with extensive validation data.

YARS2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended YARS2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7174000
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (1)
  • (2)
Cat. No. ABIN6244048
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
  • (2)
Cat. No. ABIN1882153
Quantity 400 μL
Datasheet Datasheet

Recommended YARS2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6233087
Quantity 96 tests
Datasheet Datasheet

Recommended YARS2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1325504
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125570
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2132595
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our YARS2 products

Riley, Menezes, Rudinger-Thirion, Duff, de Lonlay, Rotig, Tchan, Davis, Cooper, Christodoulou: "Phenotypic variability and identification of novel YARS2 mutations in YARS2 mitochondrial myopathy, lactic acidosis and sideroblastic anaemia." in: Orphanet journal of rare diseases, Vol. 8, pp. 193, (2014) (PubMed).

Riley, Cooper, Hickey, Rudinger-Thirion, McKenzie, Compton, Lim, Thorburn, Ryan, Giegé, Bahlo, Christodoulou: "Mutation of the mitochondrial tyrosyl-tRNA synthetase gene, YARS2, causes myopathy, lactic acidosis, and sideroblastic anemia--MLASA syndrome." in: American journal of human genetics, Vol. 87, Issue 1, pp. 52-9, (2010) (PubMed).

Bonnefond, Frugier, Touzé, Lorber, Florentz, Giegé, Sauter, Rudinger-Thirion: "Crystal structure of human mitochondrial tyrosyl-tRNA synthetase reveals common and idiosyncratic features." in: Structure (London, England : 1993), Vol. 15, Issue 11, pp. 1505-16, (2007) (PubMed).

Bonnefond, Fender, Rudinger-Thirion, Giegé, Florentz, Sissler: "Toward the full set of human mitochondrial aminoacyl-tRNA synthetases: characterization of AspRS and TyrRS." in: Biochemistry, Vol. 44, Issue 12, pp. 4805-16, (2005) (PubMed).

Bonnefond, Frugier, Giegé, Rudinger-Thirion: "Human mitochondrial TyrRS disobeys the tyrosine identity rules." in: RNA (New York, N.Y.), Vol. 11, Issue 5, pp. 558-62, (2005) (PubMed).

Synonyms and alternative names related to YARS2

tyrosyl-tRNA synthetase 2 (mitochondrial) (Yars2), tyrosyl-tRNA synthetase 2 (Yars2), tyrosyl-tRNA synthetase 2 (YARS2), 2210023C10Rik, CGI-04, MLASA2, MT-TYRRS, RGD1311696, tyrRS, TYRRS

Protein level used designations for YARS2

  • tyrosine--tRNA ligase, mitochondrial
  • tyrRS
  • tyrosyl-tRNA synthetase, mitochondrial
  • tyrosine tRNA ligase 2, mitochondrial
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