YARS Products
(Tyrosyl-tRNA Synthetase (Yars))
Categories
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine. [provided by RefSeq, Jul 2008].
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Featured YARS Categories
YARS Antibodies
High quality antibodies with extensive validation data.
YARS Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended YARS Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7443434
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (5)
Cat. No.
ABIN7173996
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
- (4)
Cat. No.
ABIN563694
Quantity
50 μg
Datasheet
Datasheet
Recommended YARS Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125569
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1325501
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN2132594
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our YARS products
: "Quantitative proteome-based systematic identification of SIRT7 substrates." in: Proteomics, Vol. 17, Issue 13-14, (2017) (PubMed).: "Alternative splicing creates two new architectures for human tyrosyl-tRNA synthetase." in: Nucleic acids research, Vol. 44, Issue 3, pp. 1247-55, (2016) (PubMed).
: "Impaired protein translation in Drosophila models for Charcot-Marie-Tooth neuropathy caused by mutant tRNA synthetases." in: Nature communications, Vol. 6, pp. 7520, (2015) (PubMed).
: "Dominant mutations in the tyrosyl-tRNA synthetase gene recapitulate in Drosophila features of human Charcot-Marie-Tooth neuropathy." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 28, pp. 11782-7, (2009) (PubMed).
: "Gain-of-function mutational activation of human tRNA synthetase procytokine." in: Chemistry & biology, Vol. 14, Issue 12, pp. 1323-33, (2007) (PubMed).
: "Disrupted function and axonal distribution of mutant tyrosyl-tRNA synthetase in dominant intermediate Charcot-Marie-Tooth neuropathy. ..." in: Nature genetics, Vol. 38, Issue 2, pp. 197-202, (2006) (PubMed).
: "Toward the full set of human mitochondrial aminoacyl-tRNA synthetases: characterization of AspRS and TyrRS." in: Biochemistry, Vol. 44, Issue 12, pp. 4805-16, (2005) (PubMed).
Synonyms and alternative names related to YARS
tyrosyl-tRNA synthetase (YARS), tyrosyl-tRNA synthetase (Yars), tyrosyl-tRNA synthetase (yars), tyrosyl-tRNA synthetase L homeolog (yars.L), tyrosyl-tRNA synthetase, putative (MAL8P1.125), tyrosine--tRNA ligase (MEFER_RS04475), Tyrosyl-tRNA synthetase (TyrRS), tyrosine--tRNA ligase, cytoplasmic (LOC413909), tyrosine--tRNA ligase, cytoplasmic (LOC100163888), tyrosyl-tRNA synthetase (LOC100282315), AL024047, anon-EST:Posey261, AU018965, cb204, CG4561, CMTDIC, cmtdic, Dmel\\CG4561, dYARS, GB10789, TYRRS, tyrrs, TyrRS, wu:fk52b08, YARS, YRS, yrs, YTS, ytsProtein level used designations for YARS
- tyrosine tRNA ligase 1, cytoplasmic
- tyrosine--tRNA ligase, cytoplasmic
- tyrosyl--tRNA ligase
- tyrosyl-tRNA synthetase, cytoplasmic
- Tyrosyl-tRNA synthetase, cytoplasmic
- tyrRS
- tyrosyl-tRNA synthetase
- Aats-tyr-PA
- CG4561-PA
- ACYPI004940
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