XRCC6 Products
(X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))
Categories
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008].
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Featured XRCC6 Categories
XRCC6 Antibodies
High quality antibodies with extensive validation data.
XRCC6 ELISA Kits
Reliable ELISA kits for a wide range of species.
XRCC6 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended XRCC6 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (2)
- (6)
Cat. No.
ABIN560973
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), IP, ICC, PLA
Validations
- (1)
- (6)
Cat. No.
ABIN2855186
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (1)
- (18)
Cat. No.
ABIN1513143
Quantity
100 μg
Datasheet
Datasheet
Recommended XRCC6 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960574
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6960575
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1381279
Quantity
96 tests
Datasheet
Datasheet
Recommended XRCC6 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1325475
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7390070
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7390073
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our XRCC6 products
: "Sp1-independent downregulation of NHEJ in response to BER deficiency." in: DNA repair, Vol. 86, pp. 102740, (2020) (PubMed).: "Noncanonical role for Ku70/80 in the prevention of allergic airway inflammation via maintenance of airway epithelial cell organelle homeostasis." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 319, Issue 4, pp. L728-L741, (2020) (PubMed).
: "System-wide Profiling of RNA-Binding Proteins Uncovers Key Regulators of Virus Infection. ..." in: Molecular cell, (2019) (PubMed).
: "Inhibition of Ku70 in a high-glucose environment aggravates bupivacaine-induced dorsal root ganglion neurotoxicity." in: Toxicology letters, Vol. 318, pp. 104-113, (2019) (PubMed).
: "Histone H3K27 methylation modulates the dynamics of FANCD2 on chromatin to facilitate NHEJ and genome stability." in: Journal of cell science, Vol. 131, Issue 12, (2018) (PubMed).
: "Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes." in: Nature communications, Vol. 7, pp. 13049, (2018) (PubMed).
: "Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans." in: Cell death and differentiation, Vol. 23, Issue 11, pp. 1765-1777, (2017) (PubMed).
: "Immortalized myogenic cells from congenital muscular dystrophy type1A patients recapitulate aberrant caspase activation in pathogenesis: a new tool for MDC1A research." in: Skeletal muscle, Vol. 3, Issue 1, pp. 28, (2014) (PubMed).
: "Use of phage display to identify novel mineralocorticoid receptor-interacting proteins." in: Molecular endocrinology (Baltimore, Md.), Vol. 28, Issue 9, pp. 1571-84, (2014) (PubMed).
: "Negative regulation of Toll-like receptor-4 signaling through the binding of glycosylphosphatidylinositol-anchored glycoprotein, CD14, with the sialic acid-binding lectin, CD33." in: The Journal of biological chemistry, Vol. 289, Issue 36, pp. 25341-50, (2014) (PubMed).
Synonyms and alternative names related to XRCC6
X-ray repair cross complementing 6 (XRCC6), ATP-dependent DNA helicase II, 70 kDa subunit (Bm1_41430), X-ray repair complementing defective repair in Chinese hamster cells 6 L homeolog (xrcc6.L), X-ray repair complementing defective repair in Chinese hamster cells 6 (Xrcc6), X-ray repair cross complementing 6 (Xrcc6), X-ray repair complementing defective repair in Chinese hamster cells 6 (XRCC6), 70kDa, CTC75, CTCBF, G22P1, G22p1, KU70, Ku70, Kup70, ML8, TLAAProtein level used designations for XRCC6
- ATP-dependent DNA helicase 2 subunit 1
- ATP-dependent DNA helicase II, 70 kDa subunit
- X-ray repair complementing defective repair in Chinese hamster cells 6 (Ku autoantigen, 70kDa)
- X-ray repair cross-complementing protein 6
- 5'-dRP lyase Ku70
- 5'-deoxyribose-5-phosphate lyase Ku70
- 70 kDa subunit of Ku antigen
- ATP-dependent DNA helicase II 70 kDa subunit
- CTC box binding factor 75 kDa subunit
- CTC box-binding factor 75 kDa subunit
- DNA repair protein XRCC6
- Ku autoantigen p70 subunit
- Ku autoantigen, 70kDa
- lupus Ku autoantigen protein p70
- thyroid autoantigen 70kD (Ku antigen)
- thyroid autoantigen 70kDa (Ku antigen)
- thyroid-lupus autoantigen p70
- 5'-dRP/AP lyase Ku70
- CTC75
- CTCBF
- Ku p70
- ku autoantigen protein p70 homolog
- thyroid autoantigen 70 kDa
- Ku70 DNA-binding component of DNA-dependent proteinkinase complex (thyroid autoantigen 70 kDa)
- thyroid autoantigen
- X-ray repair cross-complementing protein 5
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