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XRCC1 Products

(X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 1 (XRCC1))

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The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008].

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Featured XRCC1 Categories

XRCC1 Antibodies

High quality antibodies with extensive validation data.

XRCC1 ELISA Kits

Reliable ELISA kits for a wide range of species.

XRCC1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended XRCC1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN1683300
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, ELISA, FACS
Validations
  • (6)
Cat. No. ABIN3029645
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p), FACS
Validations
  • (4)
Cat. No. ABIN651735
Quantity 400 μL
Datasheet Datasheet

Recommended XRCC1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1381598
Quantity 96 tests
Datasheet Datasheet

Recommended XRCC1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1325461
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1325459
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7422274
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our XRCC1 products

Silva, Stambaugh, Yokomori, Shah, Berns: "DNA damage to a single chromosome end delays anaphase onset." in: The Journal of biological chemistry, Vol. 289, Issue 33, pp. 22771-84, (2014) (PubMed).

Ali, Jukes, Pearl, Oliver: "Specific recognition of a multiply phosphorylated motif in the DNA repair scaffold XRCC1 by the FHA domain of human PNK." in: Nucleic acids research, Vol. 37, Issue 5, pp. 1701-12, (2009) (PubMed).

Iles, Rulten, El-Khamisy, Caldecott: "APLF (C2orf13) is a novel human protein involved in the cellular response to chromosomal DNA strand breaks." in: Molecular and cellular biology, Vol. 27, Issue 10, pp. 3793-803, (2007) (PubMed).

Synonyms and alternative names related to XRCC1

X-ray repair complementing defective repair in Chinese hamster cells 1 (xrcc1), X-ray repair cross complementing 1 (XRCC1), X-ray repair complementing defective repair in Chinese hamster cells 1 (Xrcc1), X-ray repair cross complementing 1 (Xrcc1), MGC80909, rcc, RCC, Xrcc-1, xrcc1, XRCC1

Protein level used designations for XRCC1

  • X-ray repair complementing defective repair in Chinese hamster cells 1
  • X-ray repair cross complementing protein 1
  • DNA repair protein XRCC1-like
  • DNA repair protein XRCC1
  • X-ray repair cross-complementing protein 1
  • X-ray-repair, complementing defective, repair in Chinese hamster
  • x-ray repair cross-complementing group 1 protein
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