XPO1 Products
(Exportin 1 (XPO1))
Categories
The protein encoded by this gene mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. [provided by RefSeq, Jul 2008].
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Featured XPO1 Categories
XPO1 Antibodies
High quality antibodies with extensive validation data.
XPO1 ELISA Kits
Reliable ELISA kits for a wide range of species.
XPO1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended XPO1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p), ICC
Validations
- (7)
Cat. No.
ABIN4886771
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
Cat. No.
ABIN7152317
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat, Saccharomyces cerevisiae, Zebrafish (Danio rerio)
Application
WB, IHC
Validations
- (1)
- (4)
Cat. No.
ABIN2778849
Quantity
100 μL
Datasheet
Datasheet
Recommended XPO1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6955675
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1132695
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1132696
Quantity
96 tests
Datasheet
Datasheet
Recommended XPO1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN7477806
Quantity
2 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7413031
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3096383
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our XPO1 products
: "Karyopherin enrichment and compensation fortifies the nuclear pore complex against nucleocytoplasmic leakage." in: The Journal of cell biology, Vol. 221, Issue 3, (2022) (PubMed).: "Molecular profiling of anastatic cancer cells: potential role of the nuclear export pathway." in: Cellular oncology (Dordrecht), Vol. 42, Issue 5, pp. 645-661, (2020) (PubMed).
: "FUS-induced neurotoxicity in Drosophila is prevented by downregulating nucleocytoplasmic transport proteins." in: Human molecular genetics, Vol. 27, Issue 23, pp. 4103-4116, (2019) (PubMed).
: "Enhanced nuclear protein export in premature aging and rescue of the progeria phenotype by modulation of CRM1 activity. ..." in: Aging cell, Vol. 18, Issue 5, pp. e13002, (2019) (PubMed).
: "Control of nuclear β-dystroglycan content is crucial for the maintenance of nuclear envelope integrity and function." in: Biochimica et biophysica acta. Molecular cell research, Vol. 1865, Issue 2, pp. 406-420, (2018) (PubMed).
: "Inactivation of the p53-KLF4-CEBPA Axis in Acute Myeloid Leukemia." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 22, Issue 3, pp. 746-56, (2016) (PubMed).
: "Chromatin-prebound Crm1 recruits Nup98-HoxA9 fusion to induce aberrant expression of Hox cluster genes." in: eLife, Vol. 5, pp. e09540, (2016) (PubMed).
: "The second-generation exportin-1 inhibitor KPT-8602 demonstrates potent activity against acute lymphoblastic leukemia." in: Clinical cancer research : an official journal of the American Association for Cancer Research, (2016) (PubMed).
: "Identifying candidate genes for 2p15p16.1 microdeletion syndrome using clinical, genomic, and functional analysis." in: JCI insight, Vol. 1, Issue 3, pp. e85461, (2016) (PubMed).
: "SARS-CoV 9b protein diffuses into nucleus, undergoes active Crm1 mediated nucleocytoplasmic export and triggers apoptosis when retained in the nucleus." in: PLoS ONE, Vol. 6, Issue 5, pp. e19436, (2011) (PubMed).
Synonyms and alternative names related to XPO1
embargoed (emb), exportin 1 (cgd3_3060), exportin 1 (Tc00.1047053511725.150), exportin 1 (Tb11.01.5940), exportin 1 (BBOV_II007220), putative exportin 1 (LMJF_32_1100), chromosome region maintenance protein 1 (xpo1), exportin 1 (Xpo1), exportin 1 (XPO1), exportin-1 (LOC100165622), exportin 1 (CRM1 homolog, yeast) (XPO1), exportin-1 (LOC100633509), exportin 1 S homeolog (xpo1.S), 18.m06600, AA420417, CG13387, CRM1, Crm1, crm1, DCRM1, dCRM1, DDBDRAFT_0183812, DDBDRAFT_0234066, DDB_0183812, DDB_0234066, Dmel\\CG13387, Emb, emb, exp1, Exp1, exportin-1, l(2)k16715, LOC100220104, Xpo, XPO-1, XPO1, Xpo1Protein level used designations for XPO1
- CG13387-PA
- Exportin-1
- chromosomal region maintenance 1
- emb-PA
- exportin
- exportin 1
- exportin-1
- exportin 1 (CRM1 homolog, yeast)
- exportin 1-like
- exportin-1-like
- CRM1, yeast, homolog
- chromosome region maintenance 1 protein homolog
- exportin 1 (CRM1, yeast, homolog)
- exportin-1 (required for chromosome region maintenance)
- nuclear export factor CRM1
- CRM1/XPO1 protein
- exp1
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