WWTR1 Products
(WW Domain Containing Transcription Regulator 1 (WWTR1))
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This gene encodes a binding protein of the 14-3-3 family of proteins that regulate cell cycle progression, differentiation and apoptosis. The encoded protein is a transcriptional co-activator that binds to the PPXY motif present on transcription factors. The gene product contains a WW domain and, in the C-terminus, a conserved PDZ-binding motif. This gene is distinct from the gene encoding tafazzin. Both genes share the gene symbol Taz. Multiple transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010].
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Featured WWTR1 Categories
WWTR1 Antibodies
High quality antibodies with extensive validation data.
WWTR1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended WWTR1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (7)
Cat. No.
ABIN6150278
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat
Application
WB
Validations
- (5)
Cat. No.
ABIN2779708
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (3)
Cat. No.
ABIN525503
Quantity
100 μg
Datasheet
Datasheet
Recommended WWTR1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1325410
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1325412
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN2132584
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our WWTR1 products
: "TAZ couples Hippo/Wnt signalling and insulin sensitivity through Irs1 expression." in: Nature communications, Vol. 10, Issue 1, pp. 421, (2019) (PubMed).: "Programming of Schwann Cells by Lats1/2-TAZ/YAP Signaling Drives Malignant Peripheral Nerve Sheath Tumorigenesis." in: Cancer cell, Vol. 33, Issue 2, pp. 292-308.e7, (2018) (PubMed).
: "PGC-1α Controls Skeletal Stem Cell Fate and Bone-Fat Balance in Osteoporosis and Skeletal Aging by Inducing TAZ." in: Cell stem cell, Vol. 23, Issue 2, pp. 193-209.e5, (2018) (PubMed).
: "Vasodilator-stimulated phosphoprotein promotes liver metastasis of gastrointestinal cancer by activating a β1-integrin-FAK-YAP1/TAZ signaling pathway." in: NPJ precision oncology, Vol. 2, Issue 1, pp. 2, (2018) (PubMed).
: "Multiparametric Analysis of Cell Shape Demonstrates that β-PIX Directly Couples YAP Activation to Extracellular Matrix Adhesion." in: Cell systems, Vol. 4, Issue 1, pp. 84-96.e6, (2017) (PubMed).
: "A reciprocal regulatory loop between TAZ/YAP and G-protein Gαs regulates Schwann cell proliferation and myelination." in: Nature communications, Vol. 8, pp. 15161, (2017) (PubMed).
: "Lentivirus-TAZ Administration Alleviates Osteoporotic Phenotypes in the Femoral Neck of Ovariectomized Rats." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 38, Issue 1, pp. 283-94, (2016) (PubMed).
: "Role of the YAP Oncoprotein in Priming Ras-Driven Rhabdomyosarcoma." in: PLoS ONE, Vol. 10, Issue 10, pp. e0140781, (2015) (PubMed).
: "Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype." in: Oncotarget, Vol. 5, Issue 24, pp. 12509-27, (2015) (PubMed).
: "HIF-1α and TAZ serve as reciprocal co-activators in human breast cancer cells." in: Oncotarget, Vol. 6, Issue 14, pp. 11768-78, (2015) (PubMed).
Synonyms and alternative names related to WWTR1
WW domain containing transcription regulator 1 L homeolog (wwtr1.L), WW domain containing transcription regulator 1 (wwtr1), WW domain containing transcription regulator 1 (WWTR1), WW domain containing transcription regulator 1 (Wwtr1), 2310058J06Rik, 2610021I22Rik, C78399, TAZ, Taz, WWTR1Protein level used designations for WWTR1
- WW domain containing transcription regulator 1
- WW domain-containing transcription regulator protein 1
- taz
- WW domain-containing transcription regulator protein 1-like
- transcriptional co-activator with PDZ-binding motif
- transcriptional coactivator with PDZ-binding motif
- transcriptional coactivator with PDZ binding motif
- transcriptional co-activator with PDZ-binding motif (TA)Z
- transcriptional co-activator with PDZ-binding motif (TAZ)
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