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WTIP Products

(Wilms Tumor 1 Interacting Protein (WTIP))
Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, cell-cell adhesion, cell differentiation, proliferation and migration. Positively regulates microRNA (miRNA)-mediated gene silencing. Negatively regulates Hippo signaling pathway and antagonizes phosphorylation of YAP1. Acts as a transcriptional corepressor for SNAI1 and SNAI2/SLUG-dependent repression of E-cadherin transcription. Acts as a hypoxic regulator by bridging an association between the prolyl hydroxylases and VHL enabling efficient degradation of HIF1A. May monitor slit diaphragm protein assembly, a specialized adherens junction characteristic of podocytes. In case of podocyte injury, it shuttles into the nucleus and acts as a transcription regulator that represses WT1- dependent transcription regulation, thereby translating changes in slit diaphragm structure into altered gene expression and a less differentiated phenotype.

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Featured WTIP Categories

WTIP Antibodies

High quality antibodies with extensive validation data.

WTIP ELISA Kits

Reliable ELISA kits for a wide range of species.

WTIP Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended WTIP Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN1327433
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (3)
Cat. No. ABIN655782
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN1327034
Quantity 100 μg
Datasheet Datasheet

Recommended WTIP ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6971180
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1167480
Quantity 96 tests
Datasheet Datasheet

Recommended WTIP Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3096372
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2735591
Quantity 20 μg
Datasheet Datasheet

Synonyms and alternative names related to WTIP

WT1 interacting protein (Wtip), WT1 interacting protein (WTIP), WT1 interacting protein (wtip), Wilms tumor 1 interacting protein (WTIP), WT1 interacting protein L homeolog (wtip.L), WT1-interacting protein (Wtip), RGD1306411, si:ch211-79l17.3

Protein level used designations for WTIP

  • WT1-interacting protein
  • Wilms tumor protein 1-interacting protein
  • Wilms tumor protein 1-interacting protein homolog
  • WT1-interacting protein homolog
  • Wilms tumor 1 interacting protein
  • xWtip
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