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WNK3 Products

(WNK Lysine Deficient Protein Kinase 3 (WNK3))

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This gene encodes a protein belonging to the 'with no lysine' family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved lysine in subdomain I. This family member functions as a positive regulator of the transcellular Ca2+ transport pathway, and it plays a role in the increase of cell survival in a caspase-3-dependent pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010].

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Featured WNK3 Categories

WNK3 Antibodies

High quality antibodies with extensive validation data.

Recommended WNK3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Rat
Application WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro)
Validations
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Cat. No. ABIN675713
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
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Cat. No. ABIN7271382
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC
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Cat. No. ABIN7261526
Quantity 200 μL
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Recommended WNK3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
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Cat. No. ABIN1325352
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our WNK3 products

Haas, Cuddapah, Watkins, Rohn, Dy, Sontheimer: "With-No-Lysine Kinase 3 (WNK3) stimulates glioma invasion by regulating cell volume." in: American journal of physiology. Cell physiology, Vol. 301, Issue 5, pp. C1150-60, (2011) (PubMed).

Zhang, Na, Peng: "WNK3 positively regulates epithelial calcium channels TRPV5 and TRPV6 via a kinase-dependent pathway." in: American journal of physiology. Renal physiology, Vol. 295, Issue 5, pp. F1472-84, (2008) (PubMed).

Rinehart, Kahle, de Los Heros, Vazquez, Meade, Wilson, Hebert, Gimenez, Gamba, Lifton: "WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl- cotransporters required for normal blood pressure homeostasis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 46, pp. 16777-82, (2005) (PubMed).

Veríssimo, Jordan: "WNK kinases, a novel protein kinase subfamily in multi-cellular organisms." in: Oncogene, Vol. 20, Issue 39, pp. 5562-9, (2001) (PubMed).

Nagase, Kikuno, Nakayama, Hirosawa, Ohara: "Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 7, Issue 4, pp. 273-81, (2000) (PubMed).

Synonyms and alternative names related to WNK3

wu:fc63h12 (wu:fc63h12), WNK lysine deficient protein kinase 3 (LOC100363278), WNK lysine deficient protein kinase 3 (WNK3), WNK lysine deficient protein kinase 3 (Wnk3), fc63h12, PRKWNK3, Prkwnk3, RGD1563131, Wnk3-ps

Protein level used designations for WNK3

  • wu:fc63h12
  • WNK lysine deficient protein kinase 3
  • protein kinase with no lysine 3
  • serine/threonine-protein kinase WNK3
  • WNK lysine deficient protein kinase 3, pseudogene
  • protein kinase lysine-deficient 3
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