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WNK1 Products

(WNK Lysine Deficient Protein Kinase 1 (WNK1))
This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. Alternatively spliced transcript variants encoding different isoforms have been described but the full-length nature of all of them has yet to be determined.[provided by RefSeq, May 2010].

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Featured WNK1 Categories

WNK1 Antibodies

High quality antibodies with extensive validation data.

WNK1 ELISA Kits

Reliable ELISA kits for a wide range of species.

WNK1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended WNK1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
Cat. No. ABIN6256585
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7169222
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6266031
Quantity 100 μL
Datasheet Datasheet

Recommended WNK1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380142
Quantity 2 x 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN2747913
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN2747914
Quantity 96 tests
Datasheet Datasheet

Recommended WNK1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307180
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1325348
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
Cat. No. ABIN5509196
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our WNK1 products

Wade, Fang, Liu, Li, Yang, Subramanya, Maouyo, Mason, Ellison, Welling: "WNK1 kinase isoform switch regulates renal potassium excretion." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 22, pp. 8558-63, (2006) (PubMed).

Anselmo, Earnest, Chen, Juang, Kim, Zhao, Cobb: "WNK1 and OSR1 regulate the Na+, K+, 2Cl- cotransporter in HeLa cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 29, pp. 10883-8, (2006) (PubMed).

Xu, Lee, Min, Lenertz, Heise, Stippec, Goldsmith, Cobb: "WNK1: analysis of protein kinase structure, downstream targets, and potential roles in hypertension." in: Cell research, Vol. 15, Issue 1, pp. 6-10, (2005) (PubMed).

Nuaray-Fejes-Tuoth, Snyder, Fejes-Tuoth: "The kidney-specific WNK1 isoform is induced by aldosterone and stimulates epithelial sodium channel-mediated Na+ transport." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 50, pp. 17434-9, (2004) (PubMed).

Xu, Min, Stippec, Lee, Goldsmith, Cobb: "Regulation of WNK1 by an autoinhibitory domain and autophosphorylation." in: The Journal of biological chemistry, Vol. 277, Issue 50, pp. 48456-62, (2002) (PubMed).

Omasa, Chen, Mantalaris, Tsai, Wu: "Molecular cloning and sequencing of the human heme-regulated eukaryotic initiation factor 2 alpha (eIF-2 alpha) kinase from bone marrow culture." in: DNA sequence : the journal of DNA sequencing and mapping, Vol. 13, Issue 3, pp. 133-7, (2002) (PubMed).

Veríssimo, Jordan: "WNK kinases, a novel protein kinase subfamily in multi-cellular organisms." in: Oncogene, Vol. 20, Issue 39, pp. 5562-9, (2001) (PubMed).

Synonyms and alternative names related to WNK1

WNK lysine deficient protein kinase 1 (WNK1), WNK lysine deficient protein kinase 1 L homeolog (wnk1.L), WNK lysine deficient protein kinase 1 (wnk1), serine/threonine-protein kinase WNK1 (LOC100056745), WNK lysine deficient protein kinase 1 (Wnk1), with no lysine (K) kinase 1 (WNK1), 6430573H23Rik, ATWNK1, EG406236, HSAN2, hsan2, HSN2, hsn2, Hsn2, KDP, kdp, mKIAA0344, p65, pha2c, PRKWNK1, prkwnk1, Prkwnk1, PSK, psk, T9J14.14, T9J14_14, with no lysine (K) kinase 1, WNK1, ZIK4

Protein level used designations for WNK1

  • WNK lysine deficient protein kinase 1 isoform
  • erythrocyte 65 kDa protein
  • prostate-derived sterile 20-like kinase
  • protein kinase with no lysine 1
  • serine/threonine-protein kinase WNK1
  • WNK lysine deficient protein kinase 1
  • serine/threonine-protein kinase WNK1-like
  • protein kinase lysine-deficient 1
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