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WIF1 Products

(WNT Inhibitory Factor 1 (WIF1))

Categories

The protein encoded by this gene functions to inhibit WNT proteins, which are extracellular signaling molecules that play a role in embryonic development. This protein contains a WNT inhibitory factor (WIF) domain and five epidermal growth factor (EGF)-like domains, and is thought to be involved in mesoderm segmentation. This gene functions as a tumor suppressor gene, and has been found to be epigenetically silenced in various cancers. [provided by RefSeq, Jun 2010].

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Featured WIF1 Categories

WIF1 Antibodies

High quality antibodies with extensive validation data.

WIF1 ELISA Kits

Reliable ELISA kits for a wide range of species.

WIF1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended WIF1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (1)
  • (3)
Cat. No. ABIN389185
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, ICC
Validations
  • (2)
  • (3)
Cat. No. ABIN969457
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (1)
  • (2)
Cat. No. ABIN389184
Quantity 400 μL
Datasheet Datasheet

Recommended WIF1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960557
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN5510721
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN5510691
Quantity 96 tests
Datasheet Datasheet

Recommended WIF1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1791464
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1325331
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Hi-5 Cells
Validations
  • (1)
Cat. No. ABIN666765
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our WIF1 products

Zhu, Yang, Liu, Zou, Yuan, Hu et al.: "Association between Wnt inhibitory factor 1 and receptor tyrosine kinase-like orphan receptor 2 protein expression and the clinical pathological significance in benign and malignant pancreatic ..." in: Oncology letters, Vol. 13, Issue 4, pp. 2244-2252, (2017) (PubMed).

Zhou, Chen, Mashrah, Zhu, He, Hu, Xiang, Yao, Guo, Zhang: "Expression and promoter methylation of Wnt inhibitory factor-1 in the development of oral submucous fibrosis." in: Oncology reports, Vol. 34, Issue 5, pp. 2636-42, (2015) (PubMed).

Macheda, Sun, Kugathasan, Hogan, Bower, Halford, Zhang, Jacques, Lieschke, Dabdoub, Stacker: "The Wnt receptor Ryk plays a role in mammalian planar cell polarity signaling." in: The Journal of biological chemistry, Vol. 287, Issue 35, pp. 29312-23, (2012) (PubMed).

Kawakami, Hirata, Yamamura, Kikuno, Saini, Majid, Tanaka, Kawamoto, Enokida, Nakagawa, Dahiya: "Functional significance of Wnt inhibitory factor-1 gene in kidney cancer." in: Cancer research, Vol. 69, Issue 22, pp. 8603-10, (2009) (PubMed).

Veeck, Wild, Fuchs, Schüffler, Hartmann, Knüchel, Dahl: "Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (DKK3) promoter methylation in human breast cancer." in: BMC cancer, Vol. 9, pp. 217, (2009) (PubMed).

Kansara, Tsang, Kodjabachian, Sims, Trivett, Ehrich, Dobrovic, Slavin, Choong, Simmons, Dawid, Thomas: "Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in mice." in: The Journal of clinical investigation, Vol. 119, Issue 4, pp. 837-51, (2009) (PubMed).

Elston, Gill, Conaglen, Clarkson, Shaw, Law, Cook, Little, Clifton-Bligh, Robinson, McDonald: "Wnt pathway inhibitors are strongly down-regulated in pituitary tumors." in: Endocrinology, Vol. 149, Issue 3, pp. 1235-42, (2008) (PubMed).

Chan, Cui, van Hasselt, Li, Srivastava, Jin, Ng, Wang, Lee, Tsao, Zhong, Robertson, Rha, Chan, Tao: "The tumor suppressor Wnt inhibitory factor 1 is frequently methylated in nasopharyngeal and esophageal carcinomas." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 87, Issue 7, pp. 644-50, (2007) (PubMed).

Clément, Guilleret, He, Yagui-Beltrán, Lin, You, Xu, Shi, Okamoto, Benhattar, Jablons: "Epigenetic alteration of the Wnt inhibitory factor-1 promoter occurs early in the carcinogenesis of Barrett's esophagus." in: Cancer science, Vol. 99, Issue 1, pp. 46-53, (2007) (PubMed).

Synonyms and alternative names related to WIF1

protein shifted (LOC552805), wnt inhibitory factor 1 (CpipJ_CPIJ003761), WNT inhibitory factor 1 (wif1), WNT inhibitory factor 1 (WIF1), Wnt inhibitory factor 1 (Wif1), wnt inhibitory factor 1 (LOC100511326), WNT inhibitory factor 1 S homeolog (wif1.S), wnt inhibitory factor 1 (wif1), AW107799, GB10372, shf, wif-1, WIF-1, WIF1, zgc:110507

Protein level used designations for WIF1

  • shifted
  • wnt inhibitory factor 1
  • WNT inhibitory factor 1
  • wnt inhibitory factor 1-like
  • Wnt inhibitory factor-1
  • WIF-1
  • wnt inhibitory factor-1
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