WHSC2 Products
(Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2))
Categories
This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation. [provided by RefSeq, Jul 2008].
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Featured WHSC2 Categories
WHSC2 Antibodies
High quality antibodies with extensive validation data.
WHSC2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended WHSC2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS, ICC
Validations
- (2)
- (8)
Cat. No.
ABIN1724801
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS, ICC
Validations
- (2)
- (8)
Cat. No.
ABIN1724802
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
WB, ELISA, IHC, FACS, IF/ICC
Validations
- (7)
Cat. No.
ABIN1846367
Quantity
100 μL
Datasheet
Datasheet
Recommended WHSC2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1325326
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125741
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1325325
Quantity
25 μg
Datasheet
Datasheet
Latest Publications for our WHSC2 products
: "Characterizing the functional consequences of haploinsufficiency of NELF-A (WHSC2) and SLBP identifies novel cellular phenotypes in Wolf-Hirschhorn syndrome." in: Human molecular genetics, Vol. 21, Issue 10, pp. 2181-93, (2012) (PubMed).: "Cellular dynamics of the negative transcription elongation factor NELF." in: Experimental cell research, Vol. 315, Issue 10, pp. 1693-705, (2009) (PubMed).
Synonyms and alternative names related to WHSC2
Negative elongation factor A (Nelf-A), negative elongation factor complex member A (Nelfa), negative elongation factor complex member A (nelfa), negative elongation factor complex member A L homeolog (nelfa.L), negative elongation factor complex member A (NELFA), negative elongation factor complex member A, Whsc2 (Nelfa), BcDNA:SD07139, CG5874, Dmel\\CG5874, fi75f03, MGC85474, NELF, NELF-A, nelf-a, nelfa, p/okcl.15, Whsc2, whsc2, WHSC2, Whsc2h, wu:fi75f03Protein level used designations for WHSC2
- CG5874-PA
- CG5874-PB
- NELF-A
- Nelf-A-PA
- Nelf-A-PB
- negative elongation factor A
- Wolf-Hirschhorn syndrome candidate 2 protein
- Wolf-Hirschhorn syndrome candidate 2
- negative elongation factor A-like
- wolf-Hirschhorn syndrome candidate 2 protein
- Wolf-Hirschhorn syndrome candidate 2 homolog
- mWHSC2
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