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WFS1 Products

(Wolfram Syndrome 1 (WFS1))
This gene encodes a transmembrane protein, which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta-cell lines. Mutations in this gene are associated with Wolfram syndrome, also called DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), an autosomal recessive disorder. The disease affects the brain and central nervous system. Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6), also known as DFNA14 or DFNA38. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009].

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Featured WFS1 Categories

WFS1 Antibodies

High quality antibodies with extensive validation data.

WFS1 ELISA Kits

Reliable ELISA kits for a wide range of species.

WFS1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended WFS1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN1513689
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA
Validations
  • (2)
Cat. No. ABIN6266024
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validations
  • (1)
Cat. No. ABIN1385843
Quantity 100 μL
Datasheet Datasheet

Recommended WFS1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960563
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960564
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6960562
Quantity 96 tests
Datasheet Datasheet

Recommended WFS1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125742
Quantity 50 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7386020
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7386017
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our WFS1 products

Fonseca, Fukuma, Lipson, Nguyen, Allen, Oka, Urano: "WFS1 is a novel component of the unfolded protein response and maintains homeostasis of the endoplasmic reticulum in pancreatic beta-cells." in: The Journal of biological chemistry, Vol. 280, Issue 47, pp. 39609-15, (2005) (PubMed).

Takeda, Inoue, Tanizawa, Matsuzaki, Oba, Watanabe, Shinoda, Oka: "WFS1 (Wolfram syndrome 1) gene product: predominant subcellular localization to endoplasmic reticulum in cultured cells and neuronal expression in rat brain." in: Human molecular genetics, Vol. 10, Issue 5, pp. 477-84, (2001) (PubMed).

Synonyms and alternative names related to WFS1

wolframin ER transmembrane glycoprotein (Wfs1), wolframin ER transmembrane glycoprotein (WFS1), wolfram syndrome 1 (wfs1), wolframin (LOC552818), wolfram syndrome 1 (CpipJ_CPIJ013087), wolframin (WFS1), Wolfram syndrome 1 (wolframin) L homeolog (wfs1.L), AI481085, CG4917, Dmel\\CG4917, GB15257, WFRS, WFS, WFS1, wfs1, WFSL, wolframin

Protein level used designations for WFS1

  • Wolfram syndrome 1 homolog
  • wolframin
  • CG4917-PA
  • CG4917-PC
  • wfs1-PA
  • wfs1-PC
  • wolfram syndrome 1
  • Wolfram syndrome 1
  • Wolfram syndrome 1 protein homolog
  • Wolfram syndrome 1 (wolframin) L homeolog
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