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WEE2 Products

(WEE1 Homolog 2 (S. Pombe) (WEE2))

Categories

Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation.

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Featured WEE2 Categories

WEE2 Antibodies

High quality antibodies with extensive validation data.

WEE2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended WEE2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, ELISA, ICC, IF
Validations
  • (3)
Cat. No. ABIN6259536
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN3029621
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN5538689
Quantity 400 μL
Datasheet Datasheet

Recommended WEE2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6234747
Quantity 96 tests
Datasheet Datasheet

Recommended WEE2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3096407
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2735547
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our WEE2 products

Dai, Zheng, Dai, Guo, Lu, Gong, Li, Zhou, Lu, Lin: "New biallelic mutations in WEE2: expanding the spectrum of mutations that cause fertilization failure or poor fertilization." in: Fertility and sterility, Vol. 111, Issue 3, pp. 510-518, (2019) (PubMed).

Synonyms and alternative names related to WEE2

WEE1 homolog 2 (wee2), WEE1 homolog 2 (WEE2), WEE1 homolog 2 (S. pombe) (Wee2), WEE1 homolog 2 (S. pombe) (wee2), Gm1065, im:5913035, si:ch211-238n5.5, wee1, wee1-b, wee1a, wee1b, WEE1B, Wee1B, WEE2, wee2-b, wu:fi13b10, Xe-wee1, xwee1, xwee2, zgc:123074

Protein level used designations for WEE2

  • Wee1-like protein kinase 1
  • wee1-like protein kinase 2-B
  • wee1-like protein kinase 1B
  • wee1-like protein kinase 2
  • wee1B kinase
  • mWee1B
  • Wee1-like protein kinase 1B
  • Wee1-like protein kinase 2
  • Wee1B kinase
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