WDR77 Products
(WD Repeat Domain 77 (WDR77))
Categories
WDR77 is a component of the 20S PRMT5 (MIM 604045)-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins (see MIM 601061). This modification targets Sm proteins to the survival of motor neurons (SMN) complex (see MIM 600354) for assembly into small nuclear ribonucleoprotein core particles (Friesen et al., 2002 [PubMed 11756452]).[supplied by OMIM, Mar 2008].
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Featured WDR77 Categories
WDR77 Antibodies
High quality antibodies with extensive validation data.
WDR77 ELISA Kits
Reliable ELISA kits for a wide range of species.
WDR77 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended WDR77 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC (p)
Validations
- (1)
- (5)
Cat. No.
ABIN566337
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC
Validations
- (3)
Cat. No.
ABIN7159661
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
IHC, IF
Validations
- (3)
Cat. No.
ABIN7263121
Quantity
200 μL
Datasheet
Datasheet
Recommended WDR77 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1142407
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1142408
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1142409
Quantity
96 tests
Datasheet
Datasheet
Recommended WDR77 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1325277
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3083587
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3127835
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our WDR77 products
: "PRMT5- mediated symmetric arginine dimethylation is attenuated by mutant huntingtin and is impaired in Huntington's disease (HD)." in: Cell cycle (Georgetown, Tex.), Vol. 14, Issue 11, pp. 1716-29, (2015) (PubMed).: "PRMT5 is upregulated in malignant and metastatic melanoma and regulates expression of MITF and p27(Kip1.)." in: PLoS ONE, Vol. 8, Issue 9, pp. e74710, (2013) (PubMed).
Synonyms and alternative names related to WDR77
WD repeat domain 77 (WDR77), WD repeat domain 77 (Wdr77), WD repeat domain 77 S homeolog (wdr77.S), WD repeat domain 77 (wdr77), 2610003I18Rik, 2610312E17Rik, C79984, MEP-50, MEP50, mep50, Nbla10071, p44, p44/Mep50, p44/MEP50, RGD1310479, RP11-552M11.3, valois, WDR77, zgc:65780, zgc:77274Protein level used designations for WDR77
- WD repeat-containing protein 77
- androgen receptor cofactor p44
- methylosome protein 50
- MEP-50
- Ac2-269
- WD repeat domain 77
- methylosome protein 50-like
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