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WDR48 Products

(WD Repeat Domain 48 (WDR48))

Categories

Regulator of deubiquitinating complexes. Acts as a strong activator of USP1 by enhancing the USP1-mediated deubiquitination of FANCD2\; USP1 being almost inactive by itself. Also activates deubiquitinating activity of complexes containing USP12 and USP46, respectively. Activates deubiquitination by increasing the catalytic turnover without increasing the affinity of deubiquitinating enzymes for the substrate. May play a role in vesicular transport or membrane fusion events necessary for transport to lysosomes (By similarity).

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Featured WDR48 Categories

WDR48 Antibodies

High quality antibodies with extensive validation data.

WDR48 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended WDR48 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (4)
Cat. No. ABIN6150198
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, FACS, IHC (p)
Validations
  • (3)
Cat. No. ABIN654462
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC
Validations
  • (3)
Cat. No. ABIN7262753
Quantity 200 μL
Datasheet Datasheet

Recommended WDR48 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1325238
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3096352
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2735517
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our WDR48 products

Ohashi, Holthaus, Calderwood, Lai, Krastins, Sarracino, Johannsen: "The EBNA3 family of Epstein-Barr virus nuclear proteins associates with the USP46/USP12 deubiquitination complexes to regulate lymphoblastoid cell line growth." in: PLoS pathogens, Vol. 11, Issue 4, pp. e1004822, (2015) (PubMed).

Synonyms and alternative names related to WDR48

WD repeat domain 48 (WDR48), WD repeat domain 48 (Wdr48), 8430408H12Rik, mKIAA1449, P80, UAF1

Protein level used designations for WDR48

  • USP1 associated factor 1
  • USP1-associated factor 1
  • WD repeat endosomal protein
  • WD repeat-containing protein 48
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