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WDFY3 Products

(WD Repeat and FYVE Domain Containing 3 (WDFY3))

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This gene encodes a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy. This protein shuttles from the nuclear membrane to colocalize with aggregated proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy. [provided by RefSeq, May 2010].

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Featured WDFY3 Categories

WDFY3 Antibodies

High quality antibodies with extensive validation data.

Recommended WDFY3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, FACS
Validations
  • (5)
Cat. No. ABIN7193433
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, IHC
Validations
  • (3)
Cat. No. ABIN7175699
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (2)
Cat. No. ABIN949075
Quantity 100 μg
Datasheet Datasheet

Recommended WDFY3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6232836
Quantity 96 tests
Datasheet Datasheet

Recommended WDFY3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1325191
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our WDFY3 products

Wu, Adamopoulos: "Loss of WDFY3 ameliorates severity of serum transfer-induced arthritis independently of autophagy." in: Cellular immunology, Vol. 316, pp. 61-69, (2017) (PubMed).

Wu, Gu, Sarin, Zavodovskaya, Chen, Christiansen, Adamopoulos: "Autophagy-linked FYVE containing protein WDFY3 interacts with TRAF6 and modulates RANKL-induced osteoclastogenesis." in: Journal of autoimmunity, Vol. 73, pp. 73-84, (2016) (PubMed).

Suzuki, Maverakis, Sarin, Bouchareychas, Kuchroo, Nestle, Adamopoulos: "T Cell-Independent Mechanisms Associated with Neutrophil Extracellular Trap Formation and Selective Autophagy in IL-17A-Mediated Epidermal Hyperplasia." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 11, pp. 4403-4412, (2016) (PubMed).

Yao, Jia, Feathers, Lin, Khan, Klionsky, Ferguson, Zacks: "Autophagy-mediated catabolism of visual transduction proteins prevents retinal degeneration." in: Autophagy, Vol. 12, Issue 12, pp. 2439-2450, (2016) (PubMed).

Orosco, Ross, Cates, Scott, Wu, Sohn, Pleasure, Pleasure, Adamopoulos, Zarbalis: "Loss of Wdfy3 in mice alters cerebral cortical neurogenesis reflecting aspects of the autism pathology." in: Nature communications, Vol. 5, pp. 4692, (2014) (PubMed).

Park, Jang, Zuber, Lee, Cho, Matsuo, Ito, Roth: "ERADication of EDEM1 occurs by selective autophagy and requires deglycosylation by cytoplasmic peptide N-glycanase." in: Histochemistry and cell biology, Vol. 142, Issue 2, pp. 153-69, (2014) (PubMed).

Sommi, Necchi, Vitali, Montagna, De Luigi, Salmona, Ricci, Solcia: "PaCS is a novel cytoplasmic structure containing functional proteasome and inducible by cytokines/trophic factors." in: PLoS ONE, Vol. 8, Issue 12, pp. e82560, (2013) (PubMed).

Synonyms and alternative names related to WDFY3

WDFY family member 4 (WDFY4), WD repeat and FYVE domain containing 3 (WDFY3), WD repeat and FYVE domain-containing protein 3 (MGYG_03998), WD repeat and FYVE domain containing 3 (Wdfy3), 2610509D04Rik, ALFY, AW319683, B930017C24, Bchs, BWF1, D5Ertd66e, Ggtb3, mKIAA0993, ZFYVE25

Protein level used designations for WDFY3

  • WD repeat and FYVE domain containing 3
  • WD repeat and FYVE domain-containing protein 3
  • autophagy-linked FYVE protein
  • beach domain, WD repeat and FYVE domain-containing protein 1
  • galactosyltransferase 3 beta 1, 4
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