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Vpx Protein Proteins

(Vpx Protein (VPX))

Plays a role in nuclear translocation of the viral pre- integration complex (PIC), thus is required for the virus to infect non-dividing cells. Targets specific host proteins for degradation by the 26S proteasome. Acts by associating with the cellular CUL4A-DDB1 E3 ligase complex through direct interaction with host VPRPB/DCAF-1. This change in the E3 ligase substrate specificity results in the degradation of host SAMHD1. In turn, SAMHD1 depletion allows viral replication in host myeloid cells by preventing SAMHD1-mediated hydrolysis of intracellular dNTPs necessary for reverse transcription (By similarity). {ECO:0000250}.

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Vpx Protein (VPX) (AA 1-113), (full length) protein (His tag) (ABIN5710828)

VPX Origin: Human Immunodeficiency Virus (HIV) Host: Escherichia coli (E. coli) Recombinant > 90 % SDS

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recommended

Vpx Protein (VPX) (AA 1-112), (full length) protein (His-SUMO Tag) (ABIN5710778)

VPX Origin: Simian Immunodeficiency Virus (SIV) Host: Escherichia coli (E. coli) Recombinant > 90 % SDS

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Vpx Protein Proteins by Origin

Find Vpx Protein Proteins for a variety of species such as anti-Human Immunodeficiency Virus (HIV) Vpx Protein, anti-Simian Immunodeficiency Virus (SIV) Vpx Protein. The species listed below are among those available. Click on a link to go to the corresponding products.

Vpx Protein Proteins by Source

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Vpx Protein Proteins by Protein Type

Here you can find Vpx Protein Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

Vpx Protein Proteins by Application

Find Vpx Protein Proteins validated for a specific application such as SDS. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Vpx Protein Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

Vpx Protein (VPX) (AA 1-113), (full length) protein (His tag)

Reactivity Human Immunodeficiency Virus (HIV)

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN5710828

Quantity 100 μg

Datasheet Datasheet

Vpx Protein (VPX) (AA 1-112), (full length) protein (His-SUMO Tag)

Reactivity Simian Immunodeficiency Virus (SIV)

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN5710778

Quantity 100 μg

Datasheet Datasheet

Aliases for Vpx Protein Proteins

vpx protein (vpx) Proteins

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Vpx Protein Proteins by Origin

Vpx Protein Proteins by Source

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Popular Vpx Protein Proteins

Aliases for Vpx Protein Proteins

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