Vpx Protein Products
(Vpx Protein (VPX))
Categories
Plays a role in nuclear translocation of the viral pre- integration complex (PIC), thus is required for the virus to infect non-dividing cells. Targets specific host proteins for degradation by the 26S proteasome. Acts by associating with the cellular CUL4A-DDB1 E3 ligase complex through direct interaction with host VPRPB/DCAF-1. This change in the E3 ligase substrate specificity results in the degradation of host SAMHD1. In turn, SAMHD1 depletion allows viral replication in host myeloid cells by preventing SAMHD1-mediated hydrolysis of intracellular dNTPs necessary for reverse transcription (By similarity). {ECO:0000250}.
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Featured Vpx Protein Categories
Vpx Protein Antibodies
High quality antibodies with extensive validation data.
Vpx Protein Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Vpx Protein Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human Immunodeficiency Virus (HIV)
Application
ELISA, WB
Validations
- (1)
Cat. No.
ABIN7156073
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Simian Immunodeficiency Virus (SIV)
Application
ELISA
Validations
Cat. No.
ABIN7179352
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Simian Immunodeficiency Virus (SIV)
Application
ELISA
Validations
Cat. No.
ABIN7179348
Quantity
100 μg
Datasheet
Datasheet
Recommended Vpx Protein Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human Immunodeficiency Virus (HIV)
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN5710828
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Simian Immunodeficiency Virus (SIV)
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN5710778
Quantity
100 μg
Datasheet
Datasheet
Synonyms and alternative names related to Vpx Protein
vpx protein (vpx)Protein level used designations for Vpx Protein
- Viral protein X
- X ORF protein
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