VPS4B Products
(Vacuolar Protein Sorting 4 Homolog B (vps4b))
Categories
The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18\; the gene for the other resides on chromosome 16. [provided by RefSeq, Jul 2008].
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Featured VPS4B Categories
VPS4B Antibodies
High quality antibodies with extensive validation data.
VPS4B Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended VPS4B Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
Cat. No.
ABIN7175320
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
- (2)
Cat. No.
ABIN564106
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
- (1)
Cat. No.
ABIN657734
Quantity
400 μL
Datasheet
Datasheet
Recommended VPS4B ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6224706
Quantity
96 tests
Datasheet
Datasheet
Recommended VPS4B Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1325093
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN5853272
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN2132556
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our VPS4B products
: "Vacuolar Protein Sorting 4B (VPS4B) Regulates Apoptosis of Chondrocytes via p38 Mitogen-Activated Protein Kinases (MAPK) in Osteoarthritis." in: Inflammation, Vol. 40, Issue 6, pp. 1924-1932, (2018) (PubMed).: "The AAA ATPase VPS4/SKD1 regulates endosomal cholesterol trafficking independently of ESCRT-III." in: Traffic (Copenhagen, Denmark), Vol. 14, Issue 1, pp. 107-19, (2013) (PubMed).
: "Identification of an AAA ATPase VPS4B-dependent pathway that modulates epidermal growth factor receptor abundance and signaling during hypoxia." in: Molecular and cellular biology, Vol. 32, Issue 6, pp. 1124-38, (2012) (PubMed).
: "The ESCRT system is required for hepatitis C virus production." in: PLoS ONE, Vol. 6, Issue 1, pp. e14517, (2011) (PubMed).
Synonyms and alternative names related to VPS4B
vacuolar protein sorting 4 homolog B (Vps4b), vacuolar protein sorting 4 homolog B S homeolog (vps4b.S), vacuolar protein sorting 4b homolog B (S. cerevisiae) (vps4b), vacuolar protein sorting 4 homolog B (VPS4B), vacuolar protein sorting 4 homolog B (vps4b), vacuolar protein sorting 4 homolog B (S. cerevisiae) (VPS4B), vacuolar protein sorting 4B (Vps4b), 8030489C12Rik, SKD1, Skd1, SKD1B, VPS4-2, vps4a, zgc:63682Protein level used designations for VPS4B
- vacuolar protein sorting-associated protein 4B
- vacuolar protein sorting 4b
- vacuolar protein sorting 4B
- vacuolar protein sorting 4a
- vacuolar protein sorting 4 homolog B (S. cerevisiae)
- Vacuolar protein sorting-associating protein 4B
- vacuolar protein sorting factor 4B-like
- cell migration-inducing 1
- cell migration-inducing gene 1 protein
- suppressor of K(+) transport growth defect 1
- suppressor of K+ transport defect 1
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