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Vcan Products

(Versican (Vcan))
This gene is a member of the aggrecan/versican proteoglycan family. The protein encoded is a large chondroitin sulfate proteoglycan and is a major component of the extracellular matrix. This protein is involved in cell adhesion, proliferation, proliferation, migration and angiogenesis and plays a central role in tissue morphogenesis and maintenance. Mutations in this gene are the cause of Wagner syndrome type 1. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009].

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Featured Vcan Categories

Vcan Antibodies

High quality antibodies with extensive validation data.

Vcan ELISA Kits

Reliable ELISA kits for a wide range of species.

Vcan Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Vcan Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, ICC, IP
Validations
  • (6)
Cat. No. ABIN7434116
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (6)
Cat. No. ABIN741660
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (7)
Cat. No. ABIN7271309
Quantity 100 μL
Datasheet Datasheet

Recommended Vcan ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (1)
Cat. No. ABIN6960478
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6962234
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960479
Quantity 96 tests
Datasheet Datasheet

Recommended Vcan Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125707
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1324941
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7424557
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Vcan products

Gupta, Kumar, Seth, Garg, Sharma: "Targeting of stromal versican by miR-144/199 inhibits multiple myeloma by downregulating FAK/STAT3 signalling." in: RNA biology, Vol. 17, Issue 1, pp. 98-111, (2020) (PubMed).

Yang, Ma, Cao, Liu, Cao, Shen, Fu, Yan, Wang, Liu, Xiao: "CD49fhigh Defines a Distinct Skin Mesenchymal Stem Cell Population Capable of Hair Follicle Epithelial Cell Maintenance." in: The Journal of investigative dermatology, (2019) (PubMed).

Gupta, Kumar, Seth, Garg, Sati, Sharma: "Clinical significance of circulatory microRNA-203 in serum as novel potential diagnostic marker for multiple myeloma." in: Journal of cancer research and clinical oncology, Vol. 145, Issue 6, pp. 1601-1611, (2019) (PubMed).

Nakamura, Jinnin, Kudo, Inoue, Nakayama, Honda, Kajihara, Masuguchi, Fukushima, Ihn: "The role of PSMB9 upregulated by interferon signature in the pathophysiology of cutaneous lesions of dermatomyositis and systemic lupus erythematosus." in: The British journal of dermatology, Vol. 174, Issue 5, pp. 1030-41, (2016) (PubMed).

Gupta, Khan, Kumar, Kumar, Sharma: "Versican and its associated molecules: potential diagnostic markers for multiple myeloma." in: Clinica chimica acta; international journal of clinical chemistry, Vol. 442, pp. 119-24, (2015) (PubMed).

Fujii, Karpova, Asagoe, Georgiev, Dummer, Urosevic-Maiwald: "Versican upregulation in Sézary cells alters growth, motility and resistance to chemotherapy." in: Leukemia, Vol. 29, Issue 10, pp. 2024-32, (2015) (PubMed).

Van Bockstal, Lambein, Van Gele, De Vlieghere, Limame, Braems, Van den Broecke, Cocquyt, Denys, Bracke, Libbrecht, De Wever: "Differential regulation of extracellular matrix protein expression in carcinoma-associated fibroblasts by TGF-β1 regulates cancer cell spreading but not adhesion." in: Oncoscience, Vol. 1, Issue 10, pp. 634-48, (2015) (PubMed).

Cuerda-Galindo, Díaz-Gil, Palomar-Gallego, Linares-GarcíaValdecasas: "Increased fibroblast proliferation and activity after applying intense pulsed light 800-1200nm." in: Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft, (2014) (PubMed).

Desjardins, Xie, Gurler, Muralidhar, Sacks, Burdette, Barbolina: "Versican regulates metastasis of epithelial ovarian carcinoma cells and spheroids." in: Journal of ovarian research, Vol. 7, pp. 70, (2014) (PubMed).

Li, Wang, Wu, Quan, Ma, Yang, Wu, Wan: "Tumor-produced versican V1 enhances hCAP18/LL-37 expression in macrophages through activation of TLR2 and vitamin D3 signaling to promote ovarian cancer progression in vitro." in: PLoS ONE, Vol. 8, Issue 2, pp. e56616, (2013) (PubMed).

Synonyms and alternative names related to Vcan

versican a (vcana), versican (VCAN), versican (Vcan), versican (vcan), versican b (vcanb), 5430420N07Rik, 9430051N09, br146, cspg2, CSPG2, Cspg2, cspg2a, cspg2b, dcan, DPEAAE, ervr, ERVR, fb99b07, GHAP, hdf, NG2, pg-m, PG-M, PG-M(V0), PG-M(V1), sb:cb63, versican, wgn, WGN, wgn1, WGN1, wu:fb99b07, Xversican

Protein level used designations for Vcan

  • chondroitin sulfate proteoglycan 2a
  • chondroitin sulfate proteoglycan 2 (versican)
  • GHAP
  • PG-M
  • chondroitin sulfate proteoglycan core protein 2
  • glial hyaluronate-binding protein
  • large fibroblast proteoglycan
  • versican core protein
  • chondroitin sulfate proteoglycan 2
  • chondroitin sulfate proteoglycan 2b
  • dermacan
  • versican proteoglycan
  • PG-M core protein
  • Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M)
  • heart defect
  • proteoglycan
  • versican
  • versican core protein-like
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