VAMP1/VAMP2 antibody
VAMP1/VAMP2
Reactivity: Human
IHC (p)
Host: Mouse
Monoclonal
unconjugated
-
- Target
- VAMP1/VAMP2 (Vesicle-Associated Membrane Protein 1/2 (Synaptobrevin 1/2) (VAMP1/VAMP2))
- Reactivity
- Human
- Host
- Mouse
- Clonality
- Monoclonal
- Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Cross-Reactivity
- Human
- Cross-Reactivity (Details)
- Human, cattle
- Characteristics
- Sheep anti vesicle associated membrane protein 1 and 2, VAMP 1 and 2, VAMP1/2, VAMP 1/2, VAMP-1/2, Synaptobrevin 1 and 2,The MOC-1 antibody belongs to cluster 1 antibodies which react with neuroendocrine tissue (N-CAM) and in the lung typically detect SCLC and carcinoids. On the VI. International Workshop on Leukocyte Differentiation (Kobe 1996) this antibody has been designed as CD56, which is a known marker for natural killer cells (NK-cells). Lung cancer is a heterogeneous disease which may be characterized by five histopathological criteria. A distinction is drawn between squamous epithelial carcinoma, adenocarcinoma, large cell carcinoma, adenosquamous carcinoma and small cell lung carcinoma (SCLC). The first four in this line are cited as "non-SCLC" in literature. A number of antibodies have been used for the characterization and clustering of lung carcinoma during the 1. International Workshop on Small Cell Lung Cancer Antigens, London 1987. Cluster 1 membrane protein 125 - 145 kDa.
- Immunogen
- Preparation of a SCLC-derived cell line
- Isotype
- IgG
-
- Application Notes
- Heat pre-treatment of formalin-fixed tissue with Unmasking Fluid C or G,IHC(P),60 min at RT,(RTU) neat
- Restrictions
- For Research Use only
-
- Buffer
- Antibody solution in stabilizing phosphate buffer pH 7.3. Contains 0.09 % sodium azide. The volume is sufficient for at least 30 immunohistochemical tests (100 μL working solution / test). Use appropriate antibody diluent if required.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- 2-8°C
-
- Target
- VAMP1/VAMP2 (Vesicle-Associated Membrane Protein 1/2 (Synaptobrevin 1/2) (VAMP1/VAMP2))
- Alternative Name
- Vesicle Associated Membrane Protein (VAMP 1/2)
- Synonyms
- Syb-2 antibody, Syb2 antibody, sybII antibody, vesicle-associated membrane protein 2 antibody, Vamp2 antibody
- UniProt
- P13591
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