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USP8 Proteins

(Ubiquitin Specific Peptidase 8 (USP8))

Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation. Converts both 'Lys-48' an 'Lys-63'-linked ubiquitin chains. Catalytic activity is enhanced in the M phase. Involved in cell proliferation. Required to enter into S phase in response to serum stimulation. May regulate T-cell anergy mediated by RNF128 via the formation of a complex containing RNF128 and OTUB1. Probably regulates the stability of STAM2 and RASGRF1. Regulates endosomal ubiquitin dynamics, cargo sorting, membrane traffic at early endosomes, and maintenance of ESCRT-0 stability. The level of protein ubiquitination on endosomes is essential for maintaining the morphology of the organelle. Deubiquitinates EPS15 and controles tyrosine kinase stability. Removes conjugated ubiquitin from EGFR thus regulating EGFR degradation and downstream MAPK signaling. Involved in acrosome biogenesis through interaction with the spermatid ESCRT-0 complex and microtubules. Deubiquitinates BIRC6/bruce and KIF23/MKLP1.

recommended

USP8 Protein (AA 886-1096) (His tag) (ABIN7125599)

USP8 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA

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recommended

USP8 Protein (AA 777-1118) (His tag) (ABIN7398275)

USP8 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % WB, SDS, Imm, PC

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recommended

USP8 Protein (AA 1-1118) (Strep Tag) (ABIN3096238)

USP8 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant > 80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, SDS, ELISA

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USP8 Proteins by Origin

Find USP8 Proteins for a variety of species such as anti-Human USP8. The species listed below are among those available. Click on a link to go to the corresponding products.

USP8 Proteins by Source

Here you will find USP8 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

USP8 Proteins by Protein Type

Here you can find USP8 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

USP8 Proteins by Application

Find USP8 Proteins validated for a specific application such as AbP, STD, WB, ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular USP8 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

USP8 Protein (AA 886-1096) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7125599

Quantity 50 μg

Datasheet Datasheet

USP8 Protein (AA 777-1118) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7398275

Quantity 100 μg

Datasheet Datasheet

USP8 Protein (AA 1-1118) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3096238

Quantity 1 mg

Datasheet Datasheet

USP8 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2735146

Quantity 20 μg

Datasheet Datasheet

USP8 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2735145

Quantity 20 μg

Datasheet Datasheet

USP8 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2734893

Quantity 20 μg

Datasheet Datasheet

Aliases for USP8 Proteins

ubiquitin carboxyl-terminal hydrolase 8 (LOC9310109) Proteins
ubiquitin carboxyl-terminal hydrolase 8 (MGYG_00369) Proteins
ubiquitin specific peptidase 8 (USP8) Proteins
ubiquitin specific peptidase 8 (Usp8) Proteins
AI574262 Proteins
AW557536 Proteins
HumORF8 Proteins
mKIAA0055 Proteins
UBPY Proteins
Ubpy Proteins

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USP8 Proteins by Origin

USP8 Proteins by Source

USP8 Proteins by Protein Type

USP8 Proteins by Application

Popular USP8 Proteins

Aliases for USP8 Proteins

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