USP34 Products
(Ubiquitin Specific Peptidase 34 (USP34))
Categories
Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins (By similarity).
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Featured USP34 Categories
USP34 Antibodies
High quality antibodies with extensive validation data.
Recommended USP34 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse, Rat
Application
IHC, IF
Validations
- (9)
Cat. No.
ABIN7076115
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (2)
- (4)
Cat. No.
ABIN564209
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN6265924
Quantity
100 μL
Datasheet
Datasheet
Recommended USP34 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6232798
Quantity
96 tests
Datasheet
Datasheet
Recommended USP34 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324795
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our USP34 products
: "The ubiquitin specific protease USP34 protects the ubiquitin ligase gp78 from proteasomal degradation." in: Biochemical and biophysical research communications, Vol. 509, Issue 2, pp. 348-353, (2019) (PubMed).: "The ubiquitin specific protease USP34 promotes ubiquitin signaling at DNA double-strand breaks." in: Nucleic acids research, Vol. 41, Issue 18, pp. 8572-80, (2013) (PubMed).
: "The ubiquitin-specific protease USP34 regulates axin stability and Wnt/β-catenin signaling." in: Molecular and cellular biology, Vol. 31, Issue 10, pp. 2053-65, (2011) (PubMed).
: "Caveolin-1 (P132L), a common breast cancer mutation, confers mammary cell invasiveness and defines a novel stem cell/metastasis-associated gene signature." in: The American journal of pathology, Vol. 174, Issue 5, pp. 1650-62, (2009) (PubMed).
Synonyms and alternative names related to USP34
ubiquitin specific peptidase 34 (Usp34), ubiquitin specific peptidase 34 (USP34), ubiquitin specific peptidase 34 (usp34), A530081C03Rik, Murr2Protein level used designations for USP34
- ubiquitin carboxyl-terminal hydrolase 34
- ubiquitin specific protease 34
- ubiquitin specific peptidase 34
- usp36
- ubiquitin specific peptidase 34-like
- deubiquitinating enzyme 34
- ubiquitin thioesterase 34
- ubiquitin thiolesterase 34
- ubiquitin-specific-processing protease 34
- U2af1-rs1 region 2
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