USP22 Products
(Ubiquitin Specific Peptidase 22 (USP22))
Categories
Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators, where it is required for transcription (By similarity).
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Featured USP22 Categories
USP22 Antibodies
High quality antibodies with extensive validation data.
USP22 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended USP22 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
- (2)
Cat. No.
ABIN388914
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB
Validations
- (4)
Cat. No.
ABIN2787647
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7174288
Quantity
100 μg
Datasheet
Datasheet
Recommended USP22 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6223780
Quantity
96 tests
Datasheet
Datasheet
Recommended USP22 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125591
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3075103
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3122439
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our USP22 products
: "USP22 functions as an oncogenic driver in prostate cancer by regulating cell proliferation and DNA repair." in: Cancer research, (2019) (PubMed).: "Deubiquitinating enzyme USP22 positively regulates c-Myc stability and tumorigenic activity in mammalian and breast cancer cells." in: Journal of cellular physiology, Vol. 232, Issue 12, pp. 3664-3676, (2017) (PubMed).
: "lncRNA HULC promotes the growth of hepatocellular carcinoma cells via stabilizing COX-2 protein." in: Biochemical and biophysical research communications, Vol. 490, Issue 3, pp. 693-699, (2017) (PubMed).
: "Ubiquitin-specific protease 22 (USP22) positively regulates RCAN1 protein levels through RCAN1 de-ubiquitination." in: Journal of cellular physiology, Vol. 230, Issue 7, pp. 1651-60, (2015) (PubMed).
: "Decreased H2B monoubiquitination and overexpression of ubiquitin-specific protease enzyme 22 in malignant colon carcinoma." in: Human pathology, Vol. 46, Issue 7, pp. 1006-14, (2015) (PubMed).
: "The Cellular Protein Complex Associated with a Transforming Region of E1A Contains c-MYC." in: Journal of virology, Vol. 90, Issue 2, pp. 1070-9, (2015) (PubMed).
: "USP22 acts as an oncogene by regulating the stability of cyclooxygenase-2 in non-small cell lung cancer." in: Biochemical and biophysical research communications, Vol. 460, Issue 3, pp. 703-8, (2015) (PubMed).
: "USP22 regulates oncogenic signaling pathways to drive lethal cancer progression." in: Cancer research, Vol. 74, Issue 1, pp. 272-86, (2014) (PubMed).
: "A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing." in: Molecular cell, Vol. 29, Issue 1, pp. 92-101, (2008) (PubMed).
: "The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression." in: Molecular cell, Vol. 29, Issue 1, pp. 102-11, (2008) (PubMed).
Synonyms and alternative names related to USP22
ubiquitin specific peptidase 22 (USP22), ubiquitin specific peptidase 22 (Usp22), ubiquitin specific peptidase 22 (usp22), ubiquitin specific peptidase 22 S homeolog (usp22.S), AI427806, USP3L, usp3l, usp22, usp22 b, usp22-a, usp22-B, zgc:136342Protein level used designations for USP22
- deubiquitinating enzyme 22
- ubiquitin carboxyl-terminal hydrolase 22
- ubiquitin specific protease 22
- ubiquitin thioesterase 22
- ubiquitin thiolesterase 22
- ubiquitin-specific processing protease 22
- ubiquitin-specific-processing protease 22
- ubiquitin specific peptidase 22
- ubiquitin carboxyl-terminal hydrolase 22-like
- Deubiquitinating enzyme 22-B
- Ubiquitin thioesterase 22-B
- Ubiquitin-specific-processing protease 22-B
- deubiquitinating enzyme 22 B
- ubiquitin carboxyl-terminal hydrolase 22-B
- ubiquitin specific peptidase 22 b
- ubiquitin thioesterase 22 B
- ubiquitin thiolesterase 22-B
- ubiquitin-specific-processing protease 22 B
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