USP20 Products
(Ubiquitin Specific Peptidase 20 (USP20))
Categories
This gene encodes a ubiquitin specific processing protease that was first identified as a substrate of the VHL (von Hippel-Lindau disease) protein E3 ubiquitin ligase complex. In addition to being ubiquitinated by the VHL-E3 ligase complex, this enzyme deubiquitinates hypoxia-inducible factor (HIF)-1 alpha and thereby causes increased expression of HIF-1alpha targeted genes which play a role in angiogenesis, glucose metabolism, cell proliferation and metastasis. The enzyme encoded by this gene also regulates G-protein coupled receptor signaling by mediating the deubiquitination of beta-2 adrenergic receptor (ADRB2). This enzyme is a ubiquitously expressed thiolester hydrolase. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jan 2013].
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Featured USP20 Categories
USP20 Antibodies
High quality antibodies with extensive validation data.
USP20 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended USP20 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN388910
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Monkey
Application
IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN213604
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Bat, Chicken, Cow, Dog, Horse, Human, Monkey, Pig, Rabbit
Application
IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN213605
Quantity
50 μg
Datasheet
Datasheet
Recommended USP20 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6222185
Quantity
96 tests
Datasheet
Datasheet
Recommended USP20 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1324765
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324767
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3096168
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our USP20 products
: "Ubiquitin-specific peptidase 20 regulates Rad17 stability, checkpoint kinase 1 phosphorylation and DNA repair by homologous recombination." in: The Journal of biological chemistry, Vol. 289, Issue 33, pp. 22739-48, (2014) (PubMed).: "The deubiquitinases USP33 and USP20 coordinate beta2 adrenergic receptor recycling and resensitization." in: The EMBO journal, Vol. 28, Issue 12, pp. 1684-96, (2009) (PubMed).
: "Deubiquitination of type 2 iodothyronine deiodinase by von Hippel-Lindau protein-interacting deubiquitinating enzymes regulates thyroid hormone activation." in: The Journal of clinical investigation, Vol. 112, Issue 2, pp. 189-96, (2003) (PubMed).
Synonyms and alternative names related to USP20
universal stress protein (RR_RS15875), ubiquitin specific peptidase 20 (USP20), ubiquitin specific peptidase 20 (usp20), ubiquitin specific peptidase 20 (Usp20), ubiquitin specific peptidase 20 L homeolog (usp20.L), 1700055M05Rik, AI467231, hVDU2, im:7151955, lsfr3a, LSFR3A, USP20, vdu2, VDU2, Vdu2, zgc:63661Protein level used designations for USP20
- universal stress protein
- ubiquitin specific peptidase 20
- ubiquitin specific protease 20
- Deubiquitinating enzyme 20
- Ubiquitin thioesterase 20
- Ubiquitin-specific-processing protease 20
- ubiquitin carboxyl-terminal hydrolase 20
- ubiquitin thiolesterase 20
- deubiquitinating enzyme 20
- pVHL-interacting deubiquitinating enzyme 2
- ubiquitin thioesterase 20
- ubiquitin-specific-processing protease 20
- VHL-interacting deubiquitinating enzyme 2
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