USP14 Products
(Ubiquitin Specific Peptidase 14 (USP14))
Categories
This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
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Featured USP14 Categories
USP14 Antibodies
High quality antibodies with extensive validation data.
USP14 ELISA Kits
Reliable ELISA kits for a wide range of species.
USP14 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended USP14 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (1)
- (8)
Cat. No.
ABIN563939
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (1)
- (4)
Cat. No.
ABIN388902
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (5)
Cat. No.
ABIN563938
Quantity
50 μL
Datasheet
Datasheet
Recommended USP14 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960351
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5659744
Quantity
96 tests
Datasheet
Datasheet
Recommended USP14 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324754
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324752
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN2132479
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our USP14 products
: "Ubiquitin-specific protease-14 reduces cellular aggregates and protects against mutant huntingtin-induced cell degeneration: involvement of the proteasome and ER stress-activated kinase IRE1?." in: Human molecular genetics, Vol. 23, Issue 22, pp. 5928-39, (2014) (PubMed).: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, (2010) (PubMed).
: "Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment." in: Journal of proteome research, Vol. 7, Issue 12, pp. 5167-76, (2009) (PubMed).
: "The proteasome-associated deubiquitinating enzyme Usp14 is essential for the maintenance of synaptic ubiquitin levels and the development of neuromuscular junctions." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 35, pp. 10909-19, (2009) (PubMed).
: "USP14 inhibits ER-associated degradation via interaction with IRE1alpha." in: Biochemical and biophysical research communications, Vol. 379, Issue 4, pp. 995-1000, (2009) (PubMed).
: "Deubiquitination of CXCR4 by USP14 is critical for both CXCL12-induced CXCR4 degradation and chemotaxis but not ERK ativation." in: The Journal of biological chemistry, Vol. 284, Issue 9, pp. 5742-52, (2009) (PubMed).
: "Relative structural and functional roles of multiple deubiquitylating proteins associated with mammalian 26S proteasome." in: Molecular biology of the cell, Vol. 19, Issue 3, pp. 1072-82, (2008) (PubMed).
: "Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport." in: Experimental cell research, Vol. 289, Issue 2, pp. 211-21, (2003) (PubMed).
: "Human and mouse proteases: a comparative genomic approach." in: Nature reviews. Genetics, Vol. 4, Issue 7, pp. 544-58, (2003) (PubMed).
Synonyms and alternative names related to USP14
ubiquitin specific peptidase 14 (USP14), peptidase C19 family protein (usp14), ubiquitin specific peptidase 14 (Usp14), ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) (usp14), ubiquitin specific protease 14 (Bm1_28765), ubiquitin specific peptidase 14 S homeolog (usp14.S), ubiquitin specific peptidase 14 (usp14), universal stress protein (RR_RS06480), Ubiquitin carboxyl-terminal hydrolase 14 (usp-14), 2610005K12Rik, 2610037B11Rik, AW107924, ax, C78769, DDBDRAFT_0202821, DDBDRAFT_0237695, DDB_0202821, DDB_0237695, MGC69343, MGC81945, TGT, tgt, USP14, wu:fk63d09, zgc:55949Protein level used designations for USP14
- deubiquitinating enzyme 14
- tRNA-guanine transglycosylase, 60-kD subunit
- ubiquitin carboxyl-terminal hydrolase 14
- ubiquitin specific protease 14 (tRNA-guanine transglycosylase)
- ubiquitin thioesterase 14
- ubiquitin thiolesterase 14
- ubiquitin-specific processing protease 14
- ubiquitin-specific-processing protease 14
- ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
- ubiquitin domain-containing protein
- ataxia
- dUB-type TGT for deubiquitinating enzyme
- ubiquitin specific protease 14
- universal stress protein
- queuine tRNA-ribosyltransferase
- ubiquitin carboxyl-terminal hydrolase 14-like
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