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USP13 Proteins

(Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13))

Deubiquitinase that mediates deubiquitination of target proteins such as BECN1, MITF, SKP2 and USP10 and is involved in various processes such as autophagy and endoplasmic reticulum- associated degradation (ERAD). Component of a regulatory loop that of BECN1, a key regulator of autophagy, leading to stabilize the PIK3C3/VPS34-containing complexes. Also deubiquitinates USP10, an essential regulator of p53/TP53 stability. In turn, PIK3C3/VPS34- containing complexes regulate USP13 stability, suggesting the existence of a regulatory system by which PIK3C3/VPS34-containing complexes regulate p53/TP53 protein levels via USP10 and USP13. Recruited by nuclear UFD1 and mediates deubiquitination of SKP2, thereby regulating endoplasmic reticulum-associated degradation (ERAD). Mediates stabilization of SIAH2 independently of impairing SIAH2 autoubiquitination. Has a weak deubiquitinase activity in vitro and preferentially cleaves 'Lys-63'-linked polyubiquitin chains. In contrast to USP5, it is not able to mediate unanchored polyubiquitin disassembly. Able to cleave ISG15 in vitro\; however, additional experiments are required to confirm such data (By similarity).

recommended

USP13 Protein (AA 1-863) (GST tag) (ABIN1324750)

USP13 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP

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recommended

USP13 Protein (AA 1-863) (Strep Tag) (ABIN3096193)

USP13 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant > 80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

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recommended

USP13 Protein (Myc-DYKDDDDK Tag) (ABIN2712394)

USP13 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

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USP13 Proteins by Origin

Find USP13 Proteins for a variety of species such as anti-Human USP13. The species listed below are among those available. Click on a link to go to the corresponding products.

USP13 Proteins by Source

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USP13 Proteins by Protein Type

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USP13 Proteins by Application

Find USP13 Proteins validated for a specific application such as ELISA, WB, AP, AA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular USP13 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

USP13 Protein (AA 1-863) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1324750

Quantity 10 μg

Datasheet Datasheet

USP13 Protein (AA 1-863) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3096193

Quantity 1 mg

Datasheet Datasheet

USP13 Protein (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2712394

Quantity 20 μg

Datasheet Datasheet

Aliases for USP13 Proteins

ubiquitin specific peptidase 13 (USP13) Proteins
ubiquitin specific peptidase 13 (isopeptidase T-3) (Usp13) Proteins
ubiquitin specific peptidase 13 (isopeptidase T-3) (USP13) Proteins
ubiquitin specific peptidase 13 (usp13) Proteins
ubiquitin specific peptidase 13 (isopeptidase T-3) (usp13) Proteins
ubiquitin carboxyl-terminal hydrolase 13 (MGYG_01656) Proteins
universal stress protein (RR_RS02895) Proteins
2700071E21Rik Proteins
AI848077 Proteins
IsoT-3 Proteins
ISOT3 Proteins
MGC163140 Proteins
usp13 Proteins

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USP13 Proteins by Origin

USP13 Proteins by Source

USP13 Proteins by Protein Type

USP13 Proteins by Application

Popular USP13 Proteins

Aliases for USP13 Proteins

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