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USP1 Products

(Ubiquitin Specific Peptidase 1 (USP1))

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This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. The protein specifically deubiquitinates a protein in the Fanconi anemia (FA) DNA repair pathway. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008].

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Featured USP1 Categories

USP1 Antibodies

High quality antibodies with extensive validation data.

USP1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended USP1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, IP, IF
Validations
  • (4)
Cat. No. ABIN7174250
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (2)
Cat. No. ABIN675578
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN6257794
Quantity 100 μL
Datasheet Datasheet

Recommended USP1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Sandwich ELISA
Validations
Cat. No. ABIN418278
Quantity 96 tests
Datasheet Datasheet

Recommended USP1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1324739
Quantity 2 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7418269
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3096230
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our USP1 products

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Zhiqiang, Qinghui, Yongqiang, Jian, Xin, Haiying, Yuepeng: "USP1 regulates AKT phosphorylation by modulating the stability of PHLPP1 in lung cancer cells." in: Journal of cancer research and clinical oncology, Vol. 138, Issue 7, pp. 1231-8, (2012) (PubMed).

Murai, Yang, Dejsuphong, Hirota, Takeda, DAndrea: "The USP1/UAF1 complex promotes double-strand break repair through homologous recombination." in: Molecular and cellular biology, Vol. 31, Issue 12, pp. 2462-9, (2011) (PubMed).

Yang, Moldovan, Vinciguerra, Murai, Takeda, DAndrea: "Regulation of the Fanconi anemia pathway by a SUMO-like delivery network." in: Genes & development, Vol. 25, Issue 17, pp. 1847-58, (2011) (PubMed).

Lee, Yang, Cohn, Sikdar, DAndrea, Myung: "Human ELG1 regulates the level of ubiquitinated proliferating cell nuclear antigen (PCNA) through Its interactions with PCNA and USP1." in: The Journal of biological chemistry, Vol. 285, Issue 14, pp. 10362-9, (2010) (PubMed).

Puente, Sánchez, Overall, López-Otín: "Human and mouse proteases: a comparative genomic approach." in: Nature reviews. Genetics, Vol. 4, Issue 7, pp. 544-58, (2003) (PubMed).

Synonyms and alternative names related to USP1

ubiquitin specific peptidase 1 (USP1), ubiquitin specific peptidase 1 S homeolog (usp1.S), ubiquitin specific peptidase 1 (Usp1), UBP, usp1-a

Protein level used designations for USP1

  • ubiquitin carboxyl-terminal hydrolase 1
  • ubiquitin specific protease 1
  • ubiquitin specific peptidase 1
  • ubiquitin carboxyl-terminal hydrolase 1-like
  • deubiquitinating enzyme 1
  • hUBP
  • ubiquitin carboxyl terminal hydrolase 1
  • ubiquitin specific processing protease 1
  • ubiquitin thioesterase 1
  • ubiquitin thiolesterase 1
  • ubiquitin-specific-processing protease 1
  • ubiquitin specific peptdiase 1
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