Upstream Binding Transcription Factor, RNA Polymerase I Products
(Upstream Binding Transcription Factor, RNA Polymerase I (UBTF))
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This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11. [provided by RefSeq, Aug 2011].
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Upstream Binding Transcription Factor, RNA Polymerase I Antibodies
High quality antibodies with extensive validation data.
Upstream Binding Transcription Factor, RNA Polymerase I ELISA Kits
Reliable ELISA kits for a wide range of species.
Upstream Binding Transcription Factor, RNA Polymerase I Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Upstream Binding Transcription Factor, RNA Polymerase I Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IF
Validations
- (4)
- (5)
Cat. No.
ABIN563329
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IF
Validations
- (7)
Cat. No.
ABIN521228
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (5)
Cat. No.
ABIN521227
Quantity
100 μg
Datasheet
Datasheet
Recommended Upstream Binding Transcription Factor, RNA Polymerase I ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1381578
Quantity
96 tests
Datasheet
Datasheet
Recommended Upstream Binding Transcription Factor, RNA Polymerase I Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1324490
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3075235
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2734925
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our Upstream Binding Transcription Factor, RNA Polymerase I products
: "Loss of MYBBP1A Induces Cancer Stem Cell Activity in Renal Cancer." in: Cancers, Vol. 11, Issue 2, (2019) (PubMed).: "The maternal nucleolus plays a key role in centromere satellite maintenance during the oocyte to embryo transition." in: Development (Cambridge, England), Vol. 141, Issue 8, pp. 1694-704, (2014) (PubMed).
: "UBF complexes with phosphatidylinositol 4,5-bisphosphate in nucleolar organizer regions regardless of ongoing RNA polymerase I activity." in: Nucleus (Austin, Tex.), Vol. 4, Issue 6, pp. 478-86, (2014) (PubMed).
: "Role of ooplasm in nuclear and nucleolar remodeling of intergeneric somatic cell nuclear transfer embryos during the first cell cycle." in: Cellular reprogramming, Vol. 13, Issue 2, pp. 145-55, (2011) (PubMed).
: "Remodeling of ribosomal genes in somatic cells by Xenopus egg extract." in: Biochemical and biophysical research communications, Vol. 412, Issue 3, pp. 487-93, (2011) (PubMed).
: "Identification of DHX33 as a mediator of rRNA synthesis and cell growth." in: Molecular and cellular biology, Vol. 31, Issue 23, pp. 4676-91, (2011) (PubMed).
: "Nuclear and nucleolar reprogramming during the first cell cycle in bovine nuclear transfer embryos." in: Cloning and stem cells, Vol. 11, Issue 3, pp. 367-75, (2009) (PubMed).
: "Nucleologenesis and embryonic genome activation are defective in interspecies cloned embryos between bovine ooplasm and rhesus monkey somatic cells." in: BMC developmental biology, Vol. 9, pp. 44, (2009) (PubMed).
Synonyms and alternative names related to Upstream Binding Transcription Factor, RNA Polymerase I
upstream binding transcription factor, RNA polymerase I (UBTF), upstream binding transcription factor, RNA polymerase I (Ubtf), upstream binding transcription factor, RNA polymerase I (ubtf), upstream binding transcription factor, RNA polymerase I L homeolog (ubtf.L), upstream binding transcription factor, RNA polymerase I S homeolog (ubtf.S), A930005G04Rik, NOR-90, nor-90, si:dz180g5.3, Tcfubf, UBF, ubf, UBF-1, UBF1, ubf1, ubf2, Ubtf, UBTF, ubtf, wu:fj38c10, xUBF, xUBFbeta2Protein level used designations for Upstream Binding Transcription Factor, RNA Polymerase I
- 90-kDa nucleolus organizer region autoantigen
- autoantigen NOR-90
- nucleolar transcription factor 1
- UBF-1
- transcription factor UBF
- upstream-binding factor 1
- nucleolar transcription factor 1-A
- xUBF-1
- UBF-1-A
- upstream binding factor 1
- upstream-binding factor 1-A
- upstream binding transcription factor, RNA polymerase I
- nucleolar transcription factor 1-like
- UBF-1-B
- nucleolar transcription factor 1-B
- upstream-binding factor 1-B
- xUBF-2
- LOW QUALITY PROTEIN: nucleolar transcription factor 1
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