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UPF3B Proteins

(UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B))

This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome X. Two splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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UPF3B Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2735037)

UPF3B Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

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UPF3B Proteins by Origin

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UPF3B Proteins by Source

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UPF3B Proteins by Protein Type

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UPF3B Proteins by Application

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Popular UPF3B Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

UPF3B Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2735037

Quantity 20 μg

Datasheet Datasheet

Aliases for UPF3B Proteins

UPF3B, regulator of nonsense mediated mRNA decay (UPF3B) Proteins
UPF3 regulator of nonsense transcripts homolog B (yeast) (Upf3b) Proteins
UPF3B, regulator of nonsense mediated mRNA decay (Upf3b) Proteins
5730594O13Rik Proteins
AI317193 Proteins
AW541158 Proteins
HUPF3B Proteins
MRXS14 Proteins
RENT3B Proteins
RGD1560264 Proteins
UPF3X Proteins

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