UNG Products
(Uracil-DNA Glycosylase (UNG))
Categories
This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. [provided by RefSeq, Nov 2010].
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Featured UNG Categories
UNG Antibodies
High quality antibodies with extensive validation data.
UNG ELISA Kits
Reliable ELISA kits for a wide range of species.
UNG Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended UNG Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (8)
Cat. No.
ABIN7436378
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Monkey
Application
WB, IHC, IHC (p)
Validations
- (5)
Cat. No.
ABIN1501681
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IHC (p)
Validations
- (4)
Cat. No.
ABIN364332
Quantity
50 μg
Datasheet
Datasheet
Recommended UNG ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960380
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN5661967
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5659762
Quantity
96 tests
Datasheet
Datasheet
Recommended UNG Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324669
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324667
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7399127
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our UNG products
: "Monitoring of the spatial and temporal dynamics of BER/SSBR pathway proteins, including MYH, UNG2, MPG, NTH1 and NEIL1-3, during DNA replication." in: Nucleic acids research, Vol. 45, Issue 14, pp. 8291-8301, (2017) (PubMed).: "Measurement of nanoscale DNA translocation by uracil DNA glycosylase in human cells." in: Nucleic acids research, Vol. 45, Issue 21, pp. 12413-12424, (2017) (PubMed).
: "HIV-1 and HIV-2 exhibit divergent interactions with HLTF and UNG2 DNA repair proteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 27, pp. E3921-30, (2016) (PubMed).
: "The potential role of DNA methylation in abdominal aortic aneurysms." in: International journal of molecular sciences, Vol. 16, Issue 5, pp. 11259-75, (2015) (PubMed).
: "Direct infection of primary salivary gland epithelial cells by human T lymphotropic virus type I in patients with Sjögren's syndrome." in: Arthritis & rheumatology (Hoboken, N.J.), Vol. 67, Issue 4, pp. 1096-106, (2015) (PubMed).
: "Epithelial-mesenchymal transition in keratocystic odontogenic tumor: possible role in locally aggressive behavior." in: BioMed research international, Vol. 2015, pp. 168089, (2015) (PubMed).
: "Dipeptidyl peptidase 9 subcellular localization and a role in cell adhesion involving focal adhesion kinase and paxillin." in: Biochimica et biophysica acta, Vol. 1853, Issue 2, pp. 470-80, (2015) (PubMed).
: "Establishment of a dipeptidyl peptidases (DPP) 8/9 expressing cell model for evaluating the selectivity of DPP4 inhibitors." in: Journal of pharmacological and toxicological methods, Vol. 71, pp. 8-12, (2015) (PubMed).
: "Selective induction of hepatic cytochrome P450 2B activity by leelamine in vivo, as a potent novel inducer." in: Archives of pharmacal research, Vol. 38, Issue 5, pp. 725-33, (2015) (PubMed).
: "Excision of uracil from transcribed DNA negatively affects gene expression." in: The Journal of biological chemistry, Vol. 289, Issue 32, pp. 22008-18, (2014) (PubMed).
Synonyms and alternative names related to UNG
uracil-DNA glycosylase (ung), uracil-DNA glycosylase (ung2), uracil-DNA glycosylase (Ung), uracil DNA glycosylase (UNG), uracil DNA glycosylase a (unga), uracil-DNA glycosylase Ung (ung), uracil-DNA glycosylase (STY2840), uracil-DNA-glycosylase (ung), uracil DNA glycosylase (Ung), uracil DNA glycosylase L homeolog (ung.L), uracil-DNA glycosylase (ANI_1_3358024), uracil-DNA glycosylase (AOR_1_1318164), uracil glycosylase (uglA), uracil-DNA glycosylase (Arnit_2731), temporal expression: early (D4R), An02g14790, AO090001000732, BA5648, DDBDRAFT_0204444, DDBDRAFT_0214910, DDB_0204444, DDB_0214910, DGU, ECK2578, HIGM4, HIGM5, JW2564, PSPTO4236, UDG, ung, UNG1, UNG2, UNG15, zgc:56102Protein level used designations for UNG
- uracil-DNA glycosylase
- uracil-DNA glycosylase 1, uracil-DNA glycosylase 2
- UDG
- uracil-DNA glycosylase nuclear isoform
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