UNC13D Products
(Unc-13 Homolog D (UNC13D))
Categories
This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq, Jul 2008].
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Featured UNC13D Categories
UNC13D Antibodies
High quality antibodies with extensive validation data.
UNC13D Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended UNC13D Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (4)
Cat. No.
ABIN531286
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN185677
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (3)
Cat. No.
ABIN2856569
Quantity
100 μL
Datasheet
Datasheet
Recommended UNC13D ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6219996
Quantity
96 tests
Datasheet
Datasheet
Recommended UNC13D Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324647
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3096260
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2735014
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our UNC13D products
: "A Ca2+-stimulated exosome release pathway in cancer cells is regulated by Munc13-4." in: The Journal of cell biology, Vol. 217, Issue 8, pp. 2877-2890, (2018) (PubMed).: "Munc13-4 functions as a Ca(2+) sensor for homotypic secretory granule fusion to generate endosomal exocytic vacuoles." in: Molecular biology of the cell, Vol. 28, Issue 6, pp. 792-808, (2017) (PubMed).
: "Identification of a Munc13-sensitive step in chromaffin cell large dense-core vesicle exocytosis." in: eLife, Vol. 4, (2016) (PubMed).
: "Mutation spectrum in children with primary hemophagocytic lymphohistiocytosis: molecular and functional analyses of PRF1, UNC13D, STX11, and RAB27A." in: Human mutation, Vol. 27, Issue 1, pp. 62-8, (2005) (PubMed).
: "Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3)." in: Cell, Vol. 115, Issue 4, pp. 461-73, (2003) (PubMed).
Synonyms and alternative names related to UNC13D
unc-13 homolog D (UNC13D), unc-13 homolog D (C. elegans) (Unc13d), unc-13 homolog D (Unc13d), transforming growth factor beta induced (TGFBI), unc-13 homolog D (unc13d), unc-13 homolog D (un13d), 2610108D09Rik, BIGH3, CDB1, CDG2, CDGG1, CSD, CSD1, CSD2, CSD3, EBMD, FHL3, HLH3, HPLH3, Jinx, LCD1, mFLJ00067, Munc13-4, UNC13D, Unc13h4Protein level used designations for UNC13D
- protein unc-13 homolog D
- unc-13 homolog D (C. elegans)
- likely ortholog of H. sapiens unc-13 homolog D (UNC13D)
- RGD-CAP
- RGD-containing collagen-associated protein
- beta ig-h3
- kerato-epithelin
- transforming growth factor-beta-induced protein ig-h3
- protein unc-13 homolog D-like
- unc-13 homolog D
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