ULBP3 Products
(UL16 Binding Protein 3 (ULBP3))
Categories
Ligand for the NKG2D receptor, together with at least ULBP1 and ULBP2. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. Has lower affinity for NKG2D compared to ULBP1 and ULBP2 and induces weaker signaling responses than does ULBP2 or ULBP1.
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Featured ULBP3 Categories
ULBP3 Antibodies
High quality antibodies with extensive validation data.
ULBP3 ELISA Kits
Reliable ELISA kits for a wide range of species.
Recommended ULBP3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
Cat. No.
ABIN6389787
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
FACS
Validations
Cat. No.
ABIN797296
Quantity
100 tests
Datasheet
Datasheet
Reactivity
Human
Application
WB, Neut
Validations
- (1)
Cat. No.
ABIN1983478
Quantity
100 μg
Datasheet
Datasheet
Recommended ULBP3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4884984
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6386317
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1504069
Quantity
96 tests
Datasheet
Datasheet
Recommended ULBP3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
Cat. No.
ABIN7534330
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our ULBP3 products
: "Ex vivo-expanded highly purified natural killer cells in combination with temozolomide induce antitumor effects in human glioblastoma cells in vitro." in: PLoS ONE, Vol. 14, Issue 3, pp. e0212455, (2019) (PubMed).: "Expression of ligands for activating natural killer cell receptors on cell lines commonly used to assess natural killer cell function." in: BMC immunology, Vol. 20, Issue 1, pp. 8, (2019) (PubMed).
: "The pharmalogical reactivation of p53 function improves breast tumor cell lysis by granzyme B and NK cells through induction of autophagy." in: Cell death & disease, Vol. 10, Issue 10, pp. 695, (2019) (PubMed).
: "Mesenchymal stromal cells of the bone marrow and natural killer cells: cell interactions and cross modulation." in: Journal of cell communication and signaling, Vol. 12, Issue 4, pp. 673-688, (2018) (PubMed).
: "Expression Profiles of Ligands for Activating Natural Killer Cell Receptors on HIV Infected and Uninfected CD4⁺ T Cells." in: Viruses, Vol. 9, Issue 10, (2017) (PubMed).
: "T Cells Infiltrating Diseased Liver Express Ligands for the NKG2D Stress Surveillance System." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 198, Issue 3, pp. 1172-1182, (2017) (PubMed).
: "Expression and prognostic significance of unique ULBPs in pancreatic cancer." in: OncoTargets and therapy, Vol. 9, pp. 5271-9, (2016) (PubMed).
: "Combination treatment with decitabine and ionizing radiation enhances tumor cells susceptibility of T cells." in: Scientific reports, Vol. 6, pp. 32470, (2016) (PubMed).
: "Decitabine enhances anti-CD33 monoclonal antibody BI 836858-mediated natural killer ADCC against AML blasts." in: Blood, Vol. 127, Issue 23, pp. 2879-89, (2016) (PubMed).
: "NK cell activating receptor ligand expression in lymphangioleiomyomatosis is associated with lung function decline." in: JCI insight, Vol. 1, Issue 16, pp. e87270, (2016) (PubMed).
Synonyms and alternative names related to ULBP3
UL16 binding protein 3 (ULBP3), RAET1NProtein level used designations for ULBP3
- ALCAN-gamma
- N2DL-3
- NKG2D ligand 3
- NKG2DL3
- UL16-binding protein 3
- retinoic acid early transcript 1N
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