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UIMC1 Proteins

(Ubiquitin Interaction Motif Containing 1 (UIMC1))

Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Plays a central role in the BRCA1-A complex by specifically binding 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. Also weakly binds monoubiquitin but with much less affinity than 'Lys-63'-linked ubiquitin. May interact with monoubiquitinated histones H2A and H2B\; the relevance of such results is however unclear in vivo. Does not bind Lys-48'-linked ubiquitin. May indirectly Act as a transcriptional repressor by inhibiting the interaction of NR6A1 with the corepressor NCOR1 (By similarity).

recommended

UIMC1 Protein (AA 1-385) (GST tag) (ABIN1324614)

UIMC1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP

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recommended

UIMC1 Protein (AA 1-719) (Strep Tag) (ABIN3096257)

UIMC1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant > 80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

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recommended

UIMC1 Protein (AA 1-726) (His tag) (ABIN1634738)

UIMC1 Origin: Rat Host: Yeast Recombinant > 90 % ELISA

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UIMC1 Proteins by Origin

Find UIMC1 Proteins for a variety of species such as anti-Human UIMC1, anti-Rat UIMC1. The species listed below are among those available. Click on a link to go to the corresponding products.

UIMC1 Proteins by Source

Here you will find UIMC1 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

UIMC1 Proteins by Protein Type

Here you can find UIMC1 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

UIMC1 Proteins by Application

Find UIMC1 Proteins validated for a specific application such as ELISA, WB, AP, AA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular UIMC1 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

UIMC1 Protein (AA 1-385) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1324614

Quantity 10 μg

Datasheet Datasheet

UIMC1 Protein (AA 1-719) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3096257

Quantity 1 mg

Datasheet Datasheet

UIMC1 Protein (AA 1-726) (His tag)

Reactivity Rat

Source Yeast

Validations

Cat. No. ABIN1634738

Quantity 1 mg

Datasheet Datasheet

Aliases for UIMC1 Proteins

ubiquitin interaction motif containing 1 (UIMC1) Proteins
ubiquitin interaction motif containing 1 (Uimc1) Proteins
9430016E08Rik Proteins
D330018D10Rik Proteins
D630032M02Rik Proteins
RAP80 Proteins
RGD1307009 Proteins
RIP110 Proteins
Rxrip110 Proteins
UIMC1 Proteins
X2HRIP110 Proteins

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UIMC1 Proteins by Origin

UIMC1 Proteins by Source

UIMC1 Proteins by Protein Type

UIMC1 Proteins by Application

Popular UIMC1 Proteins

Aliases for UIMC1 Proteins

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