UHMK1 Products
(U2AF Homology Motif (UHM) Kinase 1 (UHMK1))
Categories
The gene encodes a serine/threonine protein kinase that promotes cell cycle progression through G1 by phosphorylation of the cyclin-dependent kinase inhibitor 1B (p27Kip1), which causes nuclear export and degradation. The encoded protein is also thought to function in the adult nervous system and the gene has been associated with schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010].
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Featured UHMK1 Categories
UHMK1 Antibodies
High quality antibodies with extensive validation data.
UHMK1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended UHMK1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (6)
- (3)
Cat. No.
ABIN392641
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7169055
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB
Validations
- (2)
Cat. No.
ABIN6243411
Quantity
400 μL
Datasheet
Datasheet
Recommended UHMK1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6225152
Quantity
96 tests
Datasheet
Datasheet
Recommended UHMK1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1324602
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324604
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3075295
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our UHMK1 products
: "Upregulated WDR5 promotes proliferation, self-renewal and chemoresistance in bladder cancer via mediating H3K4 trimethylation." in: Scientific reports, Vol. 5, pp. 8293, (2015) (PubMed).: "PI 3-kinase/Rac1 and ERK1/2 regulate FGF-2-mediated cell proliferation through phosphorylation of p27 at Ser10 by KIS and at Thr187 by Cdc25A/Cdk2." in: Investigative ophthalmology & visual science, Vol. 52, Issue 1, pp. 417-26, (2011) (PubMed).
: "Development and pharmacologic characterization of deoxybromophospha sugar derivatives with antileukemic activity." in: Investigational new drugs, Vol. 28, Issue 4, pp. 381-91, (2010) (PubMed).
: "Reduction of Raf kinase inhibitor protein expression by Bcr-Abl contributes to chronic myelogenous leukemia proliferation." in: The Journal of biological chemistry, Vol. 285, Issue 9, pp. 6585-94, (2010) (PubMed).
: "The FOXM1 transcriptional factor promotes the proliferation of leukemia cells through modulation of cell cycle progression in acute myeloid leukemia." in: Carcinogenesis, Vol. 31, Issue 11, pp. 2012-21, (2010) (PubMed).
: "Expression of kinase interacting with stathmin (KIS, UHMK1) in human brain and lymphoblasts: Effects of schizophrenia and genotype." in: Brain research, Vol. 1301, pp. 197-206, (2009) (PubMed).
: "KIS induces proliferation and the cell cycle progression through the phosphorylation of p27Kip1 in leukemia cells." in: Leukemia research, Vol. 32, Issue 9, pp. 1358-65, (2008) (PubMed).
: "FoxM1 regulates growth factor-induced expression of kinase-interacting stathmin (KIS) to promote cell cycle progression." in: The Journal of biological chemistry, Vol. 283, Issue 1, pp. 453-60, (2007) (PubMed).
: "Quantitative RT-PCR reveals a ubiquitous but preferentially neural expression of the KIS gene in rat and human." in: Brain research. Molecular brain research, Vol. 114, Issue 1, pp. 55-64, (2003) (PubMed).
: "A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression." in: The EMBO journal, Vol. 21, Issue 13, pp. 3390-401, (2002) (PubMed).
Synonyms and alternative names related to UHMK1
U2AF homology motif kinase 1 (UHMK1), U2AF homology motif (UHM) kinase 1 (uhmk1), U2AF homology motif (UHM) kinase 1 (UHMK1), U2AF homology motif (UHM) kinase 1 (Uhmk1), U2AF homology motif kinase 1 (Uhmk1), 4732477C12Rik, 4930500M09Rik, AA673513, AI449218, AU021979, KIS, KIST, Kist, P-CIP2, UHMK1, zgc:153241Protein level used designations for UHMK1
- U2AF homology motif (UHM) kinase 1
- kinase interacting stathmin
- serine/threonine-protein kinase Kist
- serine/threonine-protein kinase Kist-like
- KIS protein kinase
- PAM COOH-terminal interactor protein 2
- kinase interacting with leukemia-associated gene (stathmin)
- U2AF homology motif kinase 1
- kinase interacting with stathmin
- P-CIP2
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