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UGT2B28 Products

(UDP Glucuronosyltransferase 2 Family, Polypeptide B28 (UGT2B28))

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This gene encodes a member of the uridine diphosphoglucuronosyltransferase protein family. The encoded enzyme catalyzes the transfer of glucuronic acid from uridine diphosphoglucuronic acid to a diverse array of substrates including steroid hormones and lipid-soluble drugs. This process, known as glucuronidation, is an intermediate step in the metabolism of steroids. Two transcript variants encoding different isoforms have been found for this gene. While both isoforms are targeted to the endoplasmic reticulum, only the longer isoform appears to be active. [provided by RefSeq, May 2011].

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Featured UGT2B28 Categories

UGT2B28 Antibodies

High quality antibodies with extensive validation data.

Recommended UGT2B28 Antibodies

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Reactivity Human
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Cat. No. ABIN1881976
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Cat. No. ABIN7096454
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Cat. No. ABIN3001195
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Recommended UGT2B28 Proteins

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Reactivity Human
Source Wheat germ
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Cat. No. ABIN1330600
Quantity 10 μg
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Latest Publications for our UGT2B28 products

Setlur, Chen, Hossain, Ha, Van Doren, Stenzel, Steiner, Oldridge, Kitabayashi, Banerjee, Chen, Schäfer, Horninger, Lee, Rubin, Klocker, Demichelis: "Genetic variation of genes involved in dihydrotestosterone metabolism and the risk of prostate cancer." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 1, pp. 229-39, (2010) (PubMed).

Ménard, Eap, Harvey, Guillemette, Lévesque: "Copy-number variations (CNVs) of the human sex steroid metabolizing genes UGT2B17 and UGT2B28 and their associations with a UGT2B15 functional polymorphism." in: Human mutation, Vol. 30, Issue 9, pp. 1310-9, (2009) (PubMed).

Ross, Katzov-Eckert, Dubé, Brooks, Rassekh, Barhdadi, Feroz-Zada, Visscher, Brown, Rieder, Rogers, Phillips, Carleton, Hayden: "Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy." in: Nature genetics, Vol. 41, Issue 12, pp. 1345-9, (2009) (PubMed).

Lévesque, Turgeon, Carrier, Montminy, Beaulieu, Bélanger: "Isolation and characterization of the UGT2B28 cDNA encoding a novel human steroid conjugating UDP-glucuronosyltransferase." in: Biochemistry, Vol. 40, Issue 13, pp. 3869-81, (2001) (PubMed).

Synonyms and alternative names related to UGT2B28

UDP glucuronosyltransferase family 2 member B28 (UGT2B28)

Protein level used designations for UGT2B28

  • UDP glycosyltransferase 2 family, polypeptide B28
  • UDP-glucuronosyltransferase 2B28
  • UDPGT 2B28
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