UGT1A3 Products
(UDP Glucuronosyltransferase 1 Family, Polypeptide A3 (UGT1A3))
Categories
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. Substrates of this enzyme include estrone, 2-hydroxyestrone, and metabolites of benzo alpha-pyrene.
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Recommended UGT1A3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (1)
- (2)
Cat. No.
ABIN527150
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (1)
Cat. No.
ABIN565760
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
Cat. No.
ABIN2382200
Quantity
100 μg
Datasheet
Datasheet
Recommended UGT1A3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324575
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
Cat. No.
ABIN2752705
Quantity
2 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2734990
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our UGT1A3 products
: "Coffee induces expression of glucuronosyltransferases by the aryl hydrocarbon receptor and Nrf2 in liver and stomach." in: Gastroenterology, Vol. 139, Issue 5, pp. 1699-710, 1710.e1-2, (2010) (PubMed).Synonyms and alternative names related to UGT1A3
UDP glucuronosyltransferase 1 family, polypeptide A3 (UGT1A3), UDP-glucuronosyltransferase 1-10 (LOC100511841), UDP glucuronosyltransferase family 1 member A3 (UGT1A3), UDP glycosyltransferase 1 family, polypeptide A3 (Ugt1a3), DKFZP469K1510, UDPGT, UDPGT 1-3, UGT-1C, Ugt1, UGT1-03, UGT1.3, Ugt1a4, UGT1CProtein level used designations for UGT1A3
- UDP-glucuronosyltransferase 1-3
- UDP glucuronosyltransferase 1 family, polypeptide A3
- UDP-glucuronosyltransferase 1-3-like
- UDP-glucuronosyltransferase 1A3
- UDP glycosyltransferase 1 family, polypeptide A3
- UDP-glucuronosyltransferase 1-C
- UGT1*3
- B3
- UDP glycosyltransferase 1 family polypeptide A4
- UDPGT
- UGT1-03
- UGT1.3
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