UFD1L Products
(Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))
Categories
The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18. [provided by RefSeq, Jun 2009].
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Featured UFD1L Categories
UFD1L Antibodies
High quality antibodies with extensive validation data.
UFD1L Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended UFD1L Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IHC, ELISA, ICC
Validations
- (6)
Cat. No.
ABIN5542400
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, ICC, FACS
Validations
- (9)
Cat. No.
ABIN5542401
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IF, IHC (p), ICC
Validations
- (6)
Cat. No.
ABIN2856688
Quantity
100 μL
Datasheet
Datasheet
Recommended UFD1L Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125585
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324547
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324549
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our UFD1L products
: "VCP cooperates with UBXD1 to degrade mitochondrial outer membrane protein MCL1 in model of Huntington's disease." in: Biochimica et biophysica acta, Vol. 1863, Issue 2, pp. 552-559, (2016) (PubMed).: "SVIP is a novel VCP/p97-interacting protein whose expression causes cell vacuolation." in: Molecular biology of the cell, Vol. 14, Issue 1, pp. 262-73, (2003) (PubMed).
: "A complex of mammalian ufd1 and npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways." in: The EMBO journal, Vol. 19, Issue 10, pp. 2181-92, (2000) (PubMed).
: "A molecular pathway revealing a genetic basis for human cardiac and craniofacial defects." in: Science (New York, N.Y.), Vol. 283, Issue 5405, pp. 1158-61, (1999) (PubMed).
: "UFD1L, a developmentally expressed ubiquitination gene, is deleted in CATCH 22 syndrome." in: Human molecular genetics, Vol. 6, Issue 2, pp. 259-65, (1997) (PubMed).
Synonyms and alternative names related to UFD1L
ubiquitin recognition factor in ER associated degradation 1 (UFD1), ubiquitin recognition factor in ER-associated degradation 1 (Ufd1), ubiquitin recognition factor in ER associated degradation 1 (Ufd1), ubiquitin fusion degradation 1 like (yeast) (UFD1L), ubiquitin recognition factor in ER associated degradation 1 S homeolog (ufd1.S), ubiquitin recognition factor in ER associated degradation 1 (ufd1l), ubiquitin recognition factor in ER associated degradation 1 (ufd1), ubiquitin fusion degradation protein 1 homolog (EHI_125920), ubiquitin fusion degradation protein 1 homolog (LOC100166745), ubiquitin fusion degradation protein 1 homolog (LOC100635687), ubiquitin fusion degradation protein 1 homolog (LOC100648660), Ubiquitin Fusion Degradation (yeast UFD homolog) (ufd-1), UFD1, Ufd1, ufd1, Ufd1l, wu:fc55f04, zgc:92341Protein level used designations for UFD1L
- UB fusion protein 1
- ubiquitin fusion degradation protein 1 homolog
- ubiquitin fusion degradation 1-like protein
- fc55f04
- ubiquitin fusion degradation 1-like
- ubiquitin fusion degradation 1 like (yeast)
- ubiquitin fusion degradation 1 like
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