UCHL5 Products
(Ubiquitin Carboxyl-terminal Hydrolase L5 (UCHL5))
Categories
Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex\; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1 (By similarity).
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Featured UCHL5 Categories
UCHL5 Antibodies
High quality antibodies with extensive validation data.
UCHL5 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended UCHL5 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (3)
Cat. No.
ABIN7131538
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (fro)
Validations
- (2)
Cat. No.
ABIN388873
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (5)
- (1)
Cat. No.
ABIN1881974
Quantity
400 μL
Datasheet
Datasheet
Recommended UCHL5 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6232786
Quantity
96 tests
Datasheet
Datasheet
Recommended UCHL5 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN667457
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324519
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324521
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our UCHL5 products
: "Crystal structure of the de-ubiquitinating enzyme UCH37 (human UCH-L5) catalytic domain." in: Biochemical and biophysical research communications, Vol. 390, Issue 3, pp. 855-60, (2009) (PubMed).: "Chronic ethanol feeding affects proteasome-interacting proteins." in: Proteomics, Vol. 9, Issue 13, pp. 3609-22, (2009) (PubMed).
: "Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex." in: Molecular cell, Vol. 31, Issue 6, pp. 909-17, (2008) (PubMed).
: "Relative structural and functional roles of multiple deubiquitylating proteins associated with mammalian 26S proteasome." in: Molecular biology of the cell, Vol. 19, Issue 3, pp. 1072-82, (2008) (PubMed).
: "Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1." in: Nature cell biology, Vol. 8, Issue 9, pp. 994-1002, (2006) (PubMed).
: "A novel proteasome interacting protein recruits the deubiquitinating enzyme UCH37 to 26S proteasomes." in: The EMBO journal, Vol. 25, Issue 19, pp. 4524-36, (2006) (PubMed).
: "hRpn13/ADRM1/GP110 is a novel proteasome subunit that binds the deubiquitinating enzyme, UCH37." in: The EMBO journal, Vol. 25, Issue 24, pp. 5742-53, (2006) (PubMed).
: "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics." in: Genome research, Vol. 10, Issue 5, pp. 703-13, (2000) (PubMed).
: "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 17, pp. 9543-8, (2000) (PubMed).
Synonyms and alternative names related to UCHL5
ubiquitin carboxyl-terminal hydrolase L5 (uchl5), ubiquitin C-terminal hydrolase L5 (UCHL5), ubiquitin C-terminal hydrolase L5 L homeolog (uchl5.L), ubiquitin C-terminal hydrolase L5 (uchl5), ubiquitin carboxyl-terminal esterase L5 (Uchl5), ubiquitin C-terminal hydrolase L5 (Uchl5), 5830413B11Rik, cgi-70, CGI-70, DKFZp459M0513, INO80R, UCH-L5, uch37, Uch37, UCH37, wu:fj17f09, zgc:85615Protein level used designations for UCHL5
- ubiquitin carboxyl-terminal hydrolase isozyme L5
- ubiquitin carboxyl-terminal hydrolase L5
- UCH-L5
- ubiquitin C-terminal hydrolase 37
- ubiquitin C-terminal hydrolase UCH37
- ubiquitin thioesterase L5
- INO80 complex subunit R
- ubiquitin carboxyl-terminal esterase L5
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