UBR2 Products
(Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))
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This gene encodes an E3 ubiquitin ligase of the N-end rule proteolytic pathway that targets proteins with destabilizing N-terminal residues for polyubiquitylation and proteasome-mediated degradation. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010].
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Featured UBR2 Categories
UBR2 Antibodies
High quality antibodies with extensive validation data.
UBR2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended UBR2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, RNAi
Validations
- (5)
Cat. No.
ABIN565040
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN6265862
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN7151297
Quantity
100 μg
Datasheet
Datasheet
Recommended UBR2 Proteins
Latest Publications for our UBR2 products
: "Toll-like receptor 4 mediates Lewis lung carcinoma-induced muscle wasting via coordinate activation of protein degradation pathways." in: Scientific reports, Vol. 7, Issue 1, pp. 2273, (2019) (PubMed).: "p300 Mediates Muscle Wasting in Lewis Lung Carcinoma." in: Cancer research, Vol. 79, Issue 7, pp. 1331-1342, (2019) (PubMed).
: "Tumor induces muscle wasting in mice through releasing extracellular Hsp70 and Hsp90." in: Nature communications, Vol. 8, Issue 1, pp. 589, (2018) (PubMed).
: "p62/SQSTM1/Sequestosome-1 is an N-recognin of the N-end rule pathway which modulates autophagosome biogenesis." in: Nature communications, Vol. 8, Issue 1, pp. 102, (2017) (PubMed).
: "Activin A induces skeletal muscle catabolism via p38β mitogen-activated protein kinase." in: Journal of cachexia, sarcopenia and muscle, (2016) (PubMed).
: "Phosphorylation Impacts N-end Rule Degradation of the Proteolytically Activated Form of BMX Kinase." in: The Journal of biological chemistry, Vol. 291, Issue 43, pp. 22757-22768, (2016) (PubMed).
: "Signaling mechanism of tumor cell-induced up-regulation of E3 ubiquitin ligase UBR2." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 27, Issue 7, pp. 2893-901, (2013) (PubMed).
: "Deficiency of UBR1, a ubiquitin ligase of the N-end rule pathway, causes pancreatic dysfunction, malformations and mental retardation (Johanson-Blizzard syndrome). ..." in: Nature genetics, Vol. 37, Issue 12, pp. 1345-50, (2005) (PubMed).
Synonyms and alternative names related to UBR2
ubiquitin protein ligase E3 component n-recognin 2 (UBR2), ubiquitin protein ligase E3 component n-recognin 2 (ubr2), ubiquitin protein ligase E3 component n-recognin 2 S homeolog (ubr2.S), ubiquitin protein ligase E3 component n-recognin 2 (Ubr2), 9930021A08Rik, AI462103, AW540746, ba49a4.1, bA49A4.1, C6orf133, dJ242G1.1, dJ392M17.3, E130209G04Rik, mKIAA0349, RP3-392M17.3, si:ch211-239i4.2Protein level used designations for UBR2
- ubiquitin protein ligase E3 component n-recognin 2
- rp3-392m17.3
- E3 ubiquitin-protein ligase UBR2
- ubiquitin-protein ligase E3-alpha-2
- ubiquitin-protein ligase E3-alpha-II
- N-recognin-2
- ubiquitin ligase E3 alpha-II
Did you look for something else?
- UBR1
- UBQLNL
- UBQLN4
- UBP17
- UBP1
- UBOX5
- UBN2
- UBLCP1
- UBL7
- UBL5
- UBL4B
- UBL4A
- UBL3
- Ubiquitin-Conjugating Enzyme E2S
- Ubiquitin-Conjugating Enzyme E2N
- Ubiquitin-Conjugating Enzyme E2K
- Ubiquitin-Conjugating Enzyme E2I
- Ubiquitin-Conjugating Enzyme E2G 2
- Ubiquitin-Conjugating Enzyme E2E 3
- Ubiquitin-Conjugating Enzyme E2D 3
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