UBR1 Products
(Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1))
Categories
The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome. [provided by RefSeq, Jul 2008].
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Featured UBR1 Categories
UBR1 Antibodies
High quality antibodies with extensive validation data.
UBR1 ELISA Kits
Reliable ELISA kits for a wide range of species.
UBR1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended UBR1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (3)
Cat. No.
ABIN566929
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7151293
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Application
WB
Validations
- (2)
- (1)
Cat. No.
ABIN1881972
Quantity
400 μL
Datasheet
Datasheet
Recommended UBR1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6971040
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960348
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6222994
Quantity
96 tests
Datasheet
Datasheet
Recommended UBR1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324468
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN2751876
Quantity
5 applications
Datasheet
Datasheet
Latest Publications for our UBR1 products
: "Phosphorylation Impacts N-end Rule Degradation of the Proteolytically Activated Form of BMX Kinase." in: The Journal of biological chemistry, Vol. 291, Issue 43, pp. 22757-22768, (2016) (PubMed).: "Lack of association of genetic variation in chromosome region 15q14-22.1 with type 2 diabetes in a Japanese population." in: BMC medical genetics, Vol. 9, pp. 22, (2008) (PubMed).
: "Roles of STAT3/SOCS3 pathway in regulating the visual function and ubiquitin-proteasome-dependent degradation of rhodopsin during retinal inflammation." in: The Journal of biological chemistry, Vol. 283, Issue 36, pp. 24561-70, (2008) (PubMed).
: "Johanson-Blizzard syndrome with mild phenotypic features confirmed by UBR1 gene testing." in: World journal of gastroenterology : WJG, Vol. 14, Issue 44, pp. 6863-6, (2008) (PubMed).
: "Thiazolidinediones modulate the expression of beta-catenin and other cell-cycle regulatory proteins by targeting the F-box proteins of Skp1-Cul1-F-box protein E3 ubiquitin ligase independently of..." in: Molecular pharmacology, Vol. 72, Issue 3, pp. 725-33, (2007) (PubMed).
Synonyms and alternative names related to UBR1
Ubr1 ubiquitin ligase (Ubr1), ubiquitin protein ligase E3 component n-recognin 1 (ubr1), ubiquitin protein ligase E3 component n-recognin 1 (UBR1), E3 ubiquitin-protein ligase ubr-1 (ubr-1), ubiquitin protein ligase E3 component n-recognin 1 (Ubr1), AI504731, Dmel\\CG9086, JBS, RGD1562326, Ubr1, UBR1Protein level used designations for UBR1
- CG9086-PA
- CG9086-PB
- ubiquitin protein ligase E3 component n-recognin 1
- E3 ubiquitin-protein ligase UBR1
- E3a ligase
- N-recognin-1
- ubiquitin ligase E3 alpha-I
- ubiquitin-protein ligase E3-alpha
- ubiquitin-protein ligase E3-alpha-1
- ubiquitin-protein ligase E3-alpha-I
- E3 alpha
- ubiquitin-protein ligase e3 componen n-recognin
Did you look for something else?
- UBQLNL
- UBQLN4
- UBP17
- UBP1
- UBOX5
- UBN2
- UBLCP1
- UBL7
- UBL5
- UBL4B
- UBL4A
- UBL3
- Ubiquitin-Conjugating Enzyme E2S
- Ubiquitin-Conjugating Enzyme E2N
- Ubiquitin-Conjugating Enzyme E2K
- Ubiquitin-Conjugating Enzyme E2I
- Ubiquitin-Conjugating Enzyme E2G 2
- Ubiquitin-Conjugating Enzyme E2E 3
- Ubiquitin-Conjugating Enzyme E2D 3
- Ubiquitin Specific Peptidase 12
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