Ubiquitin-Conjugating Enzyme E2K Products
(Ubiquitin-Conjugating Enzyme E2K (UBE2K))
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The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
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Featured Ubiquitin-Conjugating Enzyme E2K Categories
Ubiquitin-Conjugating Enzyme E2K Antibodies
High quality antibodies with extensive validation data.
Ubiquitin-Conjugating Enzyme E2K ELISA Kits
Reliable ELISA kits for a wide range of species.
Ubiquitin-Conjugating Enzyme E2K Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Ubiquitin-Conjugating Enzyme E2K Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, IF, IHC (p)
Validations
- (3)
- (3)
Cat. No.
ABIN1882088
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7174460
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, WB, IHC
Validations
- (2)
Cat. No.
ABIN6265849
Quantity
100 μL
Datasheet
Datasheet
Recommended Ubiquitin-Conjugating Enzyme E2K ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6960356
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5655204
Quantity
96 tests
Datasheet
Datasheet
Recommended Ubiquitin-Conjugating Enzyme E2K Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125621
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324382
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN1097733
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our Ubiquitin-Conjugating Enzyme E2K products
: "CSF Nrf2 and HSPA8 in Parkinson's disease patients with and without LRRK2 gene mutations." in: Journal of neural transmission (Vienna, Austria : 1996), Vol. 123, Issue 3, pp. 179-87, (2016) (PubMed).: "Novel polysome messages and changes in translational activity appear after induction of adipogenesis in 3T3-L1 cells." in: BMC molecular biology, Vol. 13, pp. 9, (2012) (PubMed).
: "Hip2 interacts with and destabilizes Smac/DIABLO." in: Biochemical and biophysical research communications, Vol. 397, Issue 4, pp. 718-23, (2010) (PubMed).
: "Ubiquitin-conjugating enzyme E2-25K increases aggregate formation and cell death in polyglutamine diseases." in: Molecular and cellular neurosciences, Vol. 34, Issue 1, pp. 10-9, (2007) (PubMed).
: "E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages." in: Nature structural & molecular biology, Vol. 14, Issue 10, pp. 941-8, (2007) (PubMed).
: "E2-25K mediates US11-triggered retro-translocation of MHC class I heavy chains in a permeabilized cell system." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 31, pp. 11589-94, (2006) (PubMed).
: "NARF, an nemo-like kinase (NLK)-associated ring finger protein regulates the ubiquitylation and degradation of T cell factor/lymphoid enhancer factor (TCF/LEF)." in: The Journal of biological chemistry, Vol. 281, Issue 30, pp. 20749-60, (2006) (PubMed).
: "Regulation of macrophage-specific gene expression by degenerated lipoproteins." in: Electrophoresis, Vol. 21, Issue 2, pp. 338-46, (2000) (PubMed).
: "Induction of ubiquitin-conjugating enzyme by aggregated low density lipoprotein in human macrophages and its implications for atherosclerosis." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 20, Issue 1, pp. 128-34, (2000) (PubMed).
: "Recent advances on the pathogenesis of Huntington's disease." in: Experimental neurology, Vol. 157, Issue 1, pp. 1-18, (1999) (PubMed).
Synonyms and alternative names related to Ubiquitin-Conjugating Enzyme E2K
ubiquitin conjugating enzyme E2 K (UBE2K), ubiquitin-conjugating enzyme E2K (Ube2k), ubiquitin conjugating enzyme E2 K S homeolog (ube2k.S), ubiquitin conjugating enzyme E2 K (ube2k), ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast) (ube2kb), ubiquitin conjugating enzyme E2 K (Ube2k), ubiquitin-conjugating enzyme E2Ka (UBC1 homolog, yeast) (ube2ka), AW492011, D5Ertd601e, E2-25K, E2-25k, e2-25k, HIP2, Hip2, hip2, HYPG, Hypg, hypg, LIG, Lig, lig, UBC1, ube2k, zgc:103472, zgc:110791Protein level used designations for Ubiquitin-Conjugating Enzyme E2K
- E2(25K)
- HIP-2
- huntingtin interacting protein 2
- huntingtin-interacting protein 2
- ubiquitin carrier protein
- ubiquitin-conjugating enzyme E2 K
- ubiquitin-conjugating enzyme E2(25K)
- ubiquitin-conjugating enzyme E2-25 KDA
- ubiquitin-conjugating enzyme E2-25K
- ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)
- ubiquitin-protein ligase
- ubiquitin-conjugating enzyme E2-25 kDa
- ubiquitin-conjugating enzyme E2K (UBC1 homolog)
- huntingtin interacting protein 2-like protein
- ubiquitin-conjugating enzyme E2 K-like
Did you look for something else?
- Ubiquitin-Conjugating Enzyme E2I
- Ubiquitin-Conjugating Enzyme E2G 2
- Ubiquitin-Conjugating Enzyme E2E 3
- Ubiquitin-Conjugating Enzyme E2D 3
- Ubiquitin Specific Peptidase 12
- Ubiquitin B
- Ubiquitin Associated Protein 1
- Ubiquitin 11
- Ubiquitin +1
- Ubiquitin
- Ubiquinol-Cytochrome C Reductase Core Protein II
- Ubiquinol-Cytochrome C Reductase Complex Chaperone
- Ubiquinol-Cytochrome C Reductase Complex Assembly Factor 3
- Ubiquilin 3
- Ubiquilin 2
- Ubiquilin 1
- Ubinuclein 1
- UBIM
- UBIAD1
- UBFD1
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