Ubiquitin Products
(Ubiquitin)
Categories
Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys in protein degradation via the proteasome. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling (By similarity).
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Featured Ubiquitin Categories
Ubiquitin Antibodies
High quality antibodies with extensive validation data.
Ubiquitin ELISA Kits
Reliable ELISA kits for a wide range of species.
Ubiquitin Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Ubiquitin Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Cow
Application
WB, IHC, IF, ICC, IP
Validations
- (2)
- (6)
Cat. No.
ABIN361831
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat
Application
WB, IHC, ICC, IP
Validations
- (7)
Cat. No.
ABIN7443803
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
WB, IHC, ICC, IP
Validations
- (9)
Cat. No.
ABIN7428593
Quantity
100 μL
Datasheet
Datasheet
Recommended Ubiquitin ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6962238
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat
Analytical Method
Quantitative Competition ELISA
Validations
- (1)
Cat. No.
ABIN6960339
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN5526834
Quantity
96 tests
Datasheet
Datasheet
Recommended Ubiquitin Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125573
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125575
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7505806
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Ubiquitin products
: "The Pah-R261Q mouse reveals oxidative stress associated with amyloid-like hepatic aggregation of mutant phenylalanine hydroxylase." in: Nature communications, Vol. 12, Issue 1, pp. 2073, (2021) (PubMed).: "Extracellular ubiquitin levels are increased in coronary heart disease and associated with the severity of the disease." in: Scandinavian journal of clinical and laboratory investigation, Vol. 80, Issue 3, pp. 256-264, (2020) (PubMed).
: "M1-linked ubiquitination by LUBEL is required for inflammatory responses to oral infection in Drosophila." in: Cell death and differentiation, Vol. 26, Issue 5, pp. 860-876, (2019) (PubMed).
: "Mechanism of parkin activation by PINK1." in: Nature, Vol. 559, Issue 7714, pp. 410-414, (2019) (PubMed).
: "Small molecule modulator of aggrephagy regulates neuroinflammation to curb pathogenesis of neurodegeneration." in: EBioMedicine, Vol. 50, pp. 260-273, (2019) (PubMed).
: "Rainbow Trout Red Blood Cells Exposed to Viral Hemorrhagic Septicemia Virus Up-Regulate Antigen-Processing Mechanisms and MHC I&II, CD86, and CD83 Antigen-presenting Cell Markers." in: Cells, Vol. 8, Issue 5, (2019) (PubMed).
: "Salmonella escapes K63 ubiquitination mediated MHC II endosomal proteolysis via modulation of endosomal acidification in dendritic cells." in: Pathogens and disease, (2018) (PubMed).
: "WDR5 Facilitates Human Cytomegalovirus Replication by Promoting Capsid Nuclear Egress." in: Journal of virology, Vol. 92, Issue 9, (2018) (PubMed).
: "Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling." in: Molecular cell, Vol. 68, Issue 1, pp. 233-246.e5, (2017) (PubMed).
: "Mechanism and regulation of the Lys6-selective deubiquitinase USP30." in: Nature structural & molecular biology, Vol. 24, Issue 11, pp. 920-930, (2017) (PubMed).
Synonyms and alternative names related to Ubiquitin
Ubiquitin-63E (Ubi-p63E), Ubiquitin-5E (Ubi-p5E), transmembrane and ubiquitin-like domain containing 2 (tmub2), polyubiquitin (LOC100194618), Putative ubiquitin family protein (pco110026), ubiquitin (LOC100135798), ubiquitin B (UBB), UBiQuitin (ubq-1), Ubiquitin (LOC100190766), CG11624, CG18282, CG32744, CR32744, Dmel\\CG11624, Dmel\\CG32744, DmUb, DmUbi-p5E, DmUbi-p63E, LOC100194618, LOC100282068, si:busm1-180g5.5, si:dz180g5.5, Ub, ubi, Ubi-p, Ubi-P63e, ubi-p63E, Ubi63E, ubi63E, Ubi63p, Ubip, Ubiq, UBIQ, ubiquitin, Ubiquitin, UbpProtein level used designations for Ubiquitin
- CG11624-PA
- CG11624-PB
- CG11624-PC
- CG11624-PD
- Ubi-p63E-PA
- Ubi-p63E-PB
- Ubi-p63E-PC
- Ubi-p63E-PD
- Ubiquitin-polymeric
- polyubiquitin
- ubiquitin
- CG32744-PA
- Ubi-p5E-PA
- transmembrane and ubiquitin-like domain-containing protein 2
- polyubiquitin containing 7 ubiquitin monomers
Did you look for something else?
- Ubiquinol-Cytochrome C Reductase Core Protein II
- Ubiquinol-Cytochrome C Reductase Complex Chaperone
- Ubiquinol-Cytochrome C Reductase Complex Assembly Factor 3
- Ubiquilin 3
- Ubiquilin 2
- Ubiquilin 1
- Ubinuclein 1
- UBIM
- UBIAD1
- UBFD1
- UBE4B
- UBE4A
- UBE3D
- UBE3C
- UBE3B
- ube3a
- UBE2Z
- UBE2W
- UBE2V2
- UBE2V1
- Ubiquitin +1
- Ubiquitin 11
- Ubiquitin Associated Protein 1
- Ubiquitin B
- Ubiquitin Specific Peptidase 12
- Ubiquitin-Conjugating Enzyme E2D 3
- Ubiquitin-Conjugating Enzyme E2E 3
- Ubiquitin-Conjugating Enzyme E2G 2
- Ubiquitin-Conjugating Enzyme E2I
- Ubiquitin-Conjugating Enzyme E2K
- Ubiquitin-Conjugating Enzyme E2N
- Ubiquitin-Conjugating Enzyme E2S
- UBL3
- UBL4A
- UBL4B
- UBL5
- UBL7
- UBLCP1
- UBN2
- UBOX5
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