Ubiquilin 2 Products
(Ubiquilin 2 (UBQLN2))
Categories
This gene encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases\; and thus, are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to bind the ATPase domain of the Hsp70-like Stch protein. [provided by RefSeq, Oct 2009].
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Featured Ubiquilin 2 Categories
Ubiquilin 2 Antibodies
High quality antibodies with extensive validation data.
Ubiquilin 2 ELISA Kits
Reliable ELISA kits for a wide range of species.
Ubiquilin 2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Ubiquilin 2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (11)
- (7)
Cat. No.
ABIN565449
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (5)
Cat. No.
ABIN6149859
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7174228
Quantity
100 μg
Datasheet
Datasheet
Recommended Ubiquilin 2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6971032
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960336
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN5591997
Quantity
96 tests
Datasheet
Datasheet
Recommended Ubiquilin 2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324460
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324462
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125571
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our Ubiquilin 2 products
: "Ubiquilin 2 modulates ALS/FTD-linked FUS-RNA complex dynamics and stress granule formation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 49, pp. E11485-E11494, (2019) (PubMed).: "Mutant UBQLN2 promotes toxicity by modulating intrinsic self-assembly." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 44, pp. E10495-E10504, (2018) (PubMed).
: "Assembly and Function of Heterotypic Ubiquitin Chains in Cell-Cycle and Protein Quality Control." in: Cell, Vol. 171, Issue 4, pp. 918-933.e20, (2017) (PubMed).
: "UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome." in: Cell, Vol. 166, Issue 4, pp. 935-49, (2016) (PubMed).
: "Motor neuron disease, TDP-43 pathology, and memory deficits in mice expressing ALS-FTD-linked UBQLN2 mutations." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 47, pp. E7580-E7589, (2016) (PubMed).
: "Marked Involvement of the Striatal Efferent System in TAR DNA-Binding Protein 43 kDa-Related Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis." in: Journal of neuropathology and experimental neurology, (2016) (PubMed).
: "Drosha inclusions are new components of dipeptide-repeat protein aggregates in FTLD-TDP and ALS C9orf72 expansion cases." in: Journal of neuropathology and experimental neurology, Vol. 74, Issue 4, pp. 380-7, (2015) (PubMed).
: "Differential recruitment of UBQLN2 to nuclear inclusions in the polyglutamine diseases HD and SCA3." in: Neurobiology of disease, Vol. 82, pp. 281-8, (2015) (PubMed).
: "Viral expression of ALS-linked ubiquilin-2 mutants causes inclusion pathology and behavioral deficits in mice." in: Molecular neurodegeneration, Vol. 10, pp. 25, (2015) (PubMed).
: "Ubiquilin-1 immunoreactivity is concentrated on Hirano bodies and dystrophic neurites in Alzheimer's disease brains." in: Neuropathology and applied neurobiology, Vol. 39, Issue 7, pp. 817-30, (2014) (PubMed).
Synonyms and alternative names related to Ubiquilin 2
ubiquilin 2 (UBQLN2), ubiquilin 2 (Ubqln2), ALS15, CHAP1, Chap1, DSK2, Dsk2, HRIHFB2157, N4BP4, Plic-2, PLIC2, Plic2, RGD1563566, UBQLN2Protein level used designations for Ubiquilin 2
- Nedd4 binding protein 4
- protein linking IAP with cytoskeleton 2
- ubiquilin-2
- ubiquitin-like product Chap1/Dsk2
- Ubiquitin-related protein
- ubiquilin 2
Did you look for something else?
- Ubiquilin 1
- Ubinuclein 1
- UBIM
- UBIAD1
- UBFD1
- UBE4B
- UBE4A
- UBE3D
- UBE3C
- UBE3B
- ube3a
- UBE2Z
- UBE2W
- UBE2V2
- UBE2V1
- UBE2U
- Ube2t
- UBE2S.2
- UBE2R2
- UBE2QL1
- Ubiquilin 3
- Ubiquinol-Cytochrome C Reductase Complex Assembly Factor 3
- Ubiquinol-Cytochrome C Reductase Complex Chaperone
- Ubiquinol-Cytochrome C Reductase Core Protein II
- Ubiquitin
- Ubiquitin +1
- Ubiquitin 11
- Ubiquitin Associated Protein 1
- Ubiquitin B
- Ubiquitin Specific Peptidase 12
- Ubiquitin-Conjugating Enzyme E2D 3
- Ubiquitin-Conjugating Enzyme E2E 3
- Ubiquitin-Conjugating Enzyme E2G 2
- Ubiquitin-Conjugating Enzyme E2I
- Ubiquitin-Conjugating Enzyme E2K
- Ubiquitin-Conjugating Enzyme E2N
- Ubiquitin-Conjugating Enzyme E2S
- UBL3
- UBL4A
- UBL4B
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